哮喘联盟

   摘要
   目的：对儿童肥胖和哮喘之间关系的同期研究进行综合分析。
   背景：在过去20年里，哮喘和肥胖患病率的持续受到了广泛讨论。虽然研究已经发现，两者之间存在相关性，但护理干预的发展仍需要基于循证的研究结果。
   研究设计：2011年6月至12月对文献进行定量系统性分析。
   数据来源：采用电子数据库对1966年1月至2011年5月发表的文献进行检索。应用已阅文献列表明确新增文献。
   综述方法：采用纳入/排除标准与质量评估原则，以确保研究设计主要针对儿童肥胖和哮喘的关系。
   结果：大多数研究支持儿童肥胖和哮喘存在相关性。性别是这一相关性中最重要的效应修饰因子，与肥胖男孩相比，肥胖女孩更易患哮喘。对部分数据的协变量分析揭示，最相关的是儿童人口统计学特征，这在整个研究中存在矛盾。
   结论：本综述通过对大量的不同试验设计的综合分析来探索儿童哮喘与肥胖之间的关系。为识别高风险人群，发展护理干预措施，帮助受两种疾病困扰的儿童，尚需开展更多针对多种相关因素，例如人口统计学和行为因素的跨学科、良好设计的研究。

 

(刘国梁 审校)
J Adv Nurs. 2013 Apr 8. doi: 10.1111/jan.12129. [Epub ahead of print]
 

A systematic review of the association between obesity and asthma in children.
 

Liu PC, Kieckhefer GM, Gau BS.
 

Abstract
AIM: To provide a comprehensive integration of contemporary studies focusing on the relationship between obesity and asthma in paediatric populations.
BACKGROUND: The simultaneous increase in asthma and obesity prevalence has been widely discussed over the past 20 years. Although studies have discovered a positive correlation between the two, evidence-based findings are needed to develop nursing interventions.
DESIGN: A quantitative systematic review on the literature was conducted from June-December 2011.
DATA SOURCES: An electronic database search was conducted for studies published between January 1966-May 2011. Additional articles were identified through the reference lists of reviewed papers.
REVIEW METHODS: Inclusion/exclusion criteria and quality appraisal were applied to ensure research primarily designed to study the relationship between obesity and asthma in children was included.
RESULTS: The majority of studies support a positive association between obesity and asthma in children. Among correlates recognized as important effect modifiers, gender was the most prominent, with obese girls more likely to have asthma diagnoses than obese boys. Scrutinization of covariates in selected studies revealed that most related to children's demographic characteristics and were inconsistent across the studies.
CONCLUSIONS: This review was designed to integrate contemporary scientific findings on the association between obesity and asthma by including a large number of studies with variant research designs. To identify high-risk groups and develop nursing interventions to help children affected by both epidemics, more interdisciplinary and well-designed investigations focusing on an expanded spectrum of correlates including demographic and behavioural factors are warranted.
 

J Adv Nurs. 2013 Apr 8. doi: 10.1111/jan.12129. [Epub ahead of print]