难治性慢性咳嗽:诊断和治疗的新观点
2012/12/31
摘要
在慢性咳嗽患者中,尽管进行了正确的解剖学诊断,尚有近40%患者的咳嗽症状并未得到明显改善。这些大多数难治性哮喘患者中,喉部症状比较常见。咽喉区是食管和上下呼吸道的连接部位。慢性咳嗽患者中的反流与症状(如咽球症、咽痒和清嗓子)的关系越来越受到关注,因为采用新的药物和咽喉康复治疗联合治疗胃食管反流和喉部症状,能显著改善前期认为的难治性咳嗽,甚至可将其治愈。
(林江涛 审校)
ArchBronconeumol.2012Nov16.pii:S0300-2896(12)00280-3.doi:10.1016/j.arbres.2012.09.009. [Epubaheadofprint]
Refractory Chronic Cough: New Perspectives in Diagnosis and Treatment.
[Article in English, Spanish]
Pacheco A, Cobeta I, Wagner C.
Source
Unidad de Tos Crónica y Asma de Difícil Control, Servicio de Neumología, Hospital Ramón y Cajal, Madrid, España. Electronic address: apacheco.hrc@salud.madrid.org.
Abstract
In patients with chronic cough, nearly 40% of the population does not experience definitive improvement of their cough despite correctly applying the anatomic diagnosis. In many of these patients with refractory cough, laryngeal symptoms are frequent. The region of the larynx/pharynx is configured as a bridge between the esophagus and the upper and lower respiratory tract. The association of reflux in patients with chronic cough and symptoms such as globus pharyngis, itchiness or the need to clear one’s throat have recently been given attention due to the possibility of joint therapeutic intervention of the gastroesophageal reflux and larynx, both with new medications as well as with laryngeal rehabilitation therapies, with observed benefits in the disappearance of chronic cough in cases that had been previously labeled as refractory.
ArchBronconeumol.2012Nov16.pii:S0300-2896(12)00280-3.doi:10.1016/j.arbres.2012.09.009. [Epubaheadofprint]
上一篇:
雾化吸入治疗成人难治性慢性咳嗽的长期安全性:系列病例报道
下一篇:
急性咳嗽:以色列城市健康中心中的抗菌药物和医疗服务使用情况