1993年至2007年西班牙加利西亚省哮喘死亡率趋势
2012/12/31
摘要
前言：在过去数年间，至少在西方国家，哮喘相关死亡呈现下降趋势，但不同人群之间存在显著差异。本试验旨在描述1993年至2007年间本社区哮喘相关死亡率的趋势，并对其有关因素进行分析。
方法：所有哮喘导致的死亡病例入选本研究。死亡数据来自于死亡注册网的官方死亡证明。采用泊松广义线性模型，估计基于日历年的死亡相对风险、社会人口统计学变量（年龄和性别）、季节、每周天数。
结果：在为期15年的研究期内，1180名患者死于哮喘，死亡主要发生在冬季（34.5%），主要为女性（64.5%）和年长者（≥65岁：84.6%）。在研究期内，所有年龄组的死亡率存在下降趋势。35～64岁年龄组和>65岁的男性，死亡率存在显著下降。
结论：本社区哮喘相关死亡呈现显著变化，过去数年中，哮喘有关呈现下降趋势。年长、女性和冬季与较高的哮喘相关死亡有关。
（刘国梁 审校）
J Asthma. 2012 Oct 29. [Epub ahead of print]
Trends of Asthma Mortality in Galicia from 1993 to 2007.
Gonzalez-Barcala FJ, Aboal J, Carreira JM, Rodriguez-Alvarez MX, Puga A, Sanjose E, Pintos M, Valdes L.
Source
Department of Respiratory Diseases, University Hospital of Santiago de Compostela , Santiago de Compostela , Spain.
Abstract
INTRODUCTION：In the past few years, deaths due to asthma appear to decrease at least in Western countries; but there are significant variations between populations. The aim of this study is to describe the trends in deaths due to asthma between 1993 and 2007 in our community and to analyze any factors associated with this.
METHODS：All cases, which had asthma as a cause of death, were included in the study. The mortality data were obtained from the official death certificate from the Deaths Register. Mortality relative risk, based on the calendar year, sociodemographic variables (age and gender), seasons, and days of the week, were estimated using a Poisson generalized linear model with a log-link.
RESULTS：In the 15 years of the study period, a total of 1180 people had died due to asthma, mainly in winter (34.5%), women (64.5%), and advanced age (65 years or above; 84.6%). A tendency of decreased mortality in all age groups was observed during the period of the study, which was significant in both the sexes in the 35- to 64-year-old age group, and in males above 65 years.
CONCLUSION：Death due to asthma is changing favorably in our community, with a tendency to decrease in the past few years. Advanced age, being female, and the winter period are associated with a higher mortality rate due to asthma.
J Asthma. 2012 Oct 29. [Epub ahead of print]
前言：在过去数年间，至少在西方国家，哮喘相关死亡呈现下降趋势，但不同人群之间存在显著差异。本试验旨在描述1993年至2007年间本社区哮喘相关死亡率的趋势，并对其有关因素进行分析。
方法：所有哮喘导致的死亡病例入选本研究。死亡数据来自于死亡注册网的官方死亡证明。采用泊松广义线性模型，估计基于日历年的死亡相对风险、社会人口统计学变量（年龄和性别）、季节、每周天数。
结果：在为期15年的研究期内，1180名患者死于哮喘，死亡主要发生在冬季（34.5%），主要为女性（64.5%）和年长者（≥65岁：84.6%）。在研究期内，所有年龄组的死亡率存在下降趋势。35～64岁年龄组和>65岁的男性，死亡率存在显著下降。
结论：本社区哮喘相关死亡呈现显著变化，过去数年中，哮喘有关呈现下降趋势。年长、女性和冬季与较高的哮喘相关死亡有关。
（刘国梁 审校）
J Asthma. 2012 Oct 29. [Epub ahead of print]
Trends of Asthma Mortality in Galicia from 1993 to 2007.
Gonzalez-Barcala FJ, Aboal J, Carreira JM, Rodriguez-Alvarez MX, Puga A, Sanjose E, Pintos M, Valdes L.
Source
Department of Respiratory Diseases, University Hospital of Santiago de Compostela , Santiago de Compostela , Spain.
Abstract
INTRODUCTION：In the past few years, deaths due to asthma appear to decrease at least in Western countries; but there are significant variations between populations. The aim of this study is to describe the trends in deaths due to asthma between 1993 and 2007 in our community and to analyze any factors associated with this.
METHODS：All cases, which had asthma as a cause of death, were included in the study. The mortality data were obtained from the official death certificate from the Deaths Register. Mortality relative risk, based on the calendar year, sociodemographic variables (age and gender), seasons, and days of the week, were estimated using a Poisson generalized linear model with a log-link.
RESULTS：In the 15 years of the study period, a total of 1180 people had died due to asthma, mainly in winter (34.5%), women (64.5%), and advanced age (65 years or above; 84.6%). A tendency of decreased mortality in all age groups was observed during the period of the study, which was significant in both the sexes in the 35- to 64-year-old age group, and in males above 65 years.
CONCLUSION：Death due to asthma is changing favorably in our community, with a tendency to decrease in the past few years. Advanced age, being female, and the winter period are associated with a higher mortality rate due to asthma.
J Asthma. 2012 Oct 29. [Epub ahead of print]
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