哮喘与龋齿
2012/08/28
摘要
数据来源:Medline、政府报道和会议记录。
对象选择:研究哮喘和龋齿相关性的、有独立研究人群的、有具体哮喘和龋齿定义的、有适当龋齿检测的病例-对照、队列或横断面研究。
数据提取和合成:由2位作者对数据进行独立提取,采用Newcastle-Ottawa质量评价量表对研究质量进行评价。采用固定和随机效应模型进行分析。同时评价异质性和发表偏倚。
结果:入选了18项研究入选,其中11项试验对乳齿进行研究,而15项试验涉及恒牙研究。随机效应模型显示,在乳齿和恒牙患者中,哮喘与龋齿呈显著相关,优势比分别为2.73(95% CI: 1.61, 4.64)和2.04(95% CI: 1.44, 2.89)。
结论:本研究结果显示,不管乳齿还是恒牙受试者,哮喘能将龋齿患病的风险增加2倍。诊断和模拟的发表偏倚显示,恒牙受试者(而非乳齿受试者)的优势比有高估的可能。对于哮喘患者,临床医生和牙科医生应该推荐某些措施预防龋齿。
(林江涛 审校)
Evid Based Dent. 2012;13(2):41. doi: 10.1038/sj.ebd.6400854.
Asthma and dental caries.
Matthews J.
Source
General dentist - Los Alamos, New Mexico, USA.
Abstract
DATA SOURCES: Medline,government reports and conference proceedings were searched. STUDY SELECTION:Case-control, cohort or cross sectional studies were included if they provided relevant and applicable quantitative information on the relation between asthma and caries, had an independent study population and adequate definitions of asthma and caries and appropriate measurement of caries.
DATA EXTRACTION AND SYNTHESIS:Data were extracted independently by two reviewers and quality was assessed using the Newcastle-Ottawa Quality Assessment Scale. Fixed- and random-effects models were used for the analyses. Heterogeneity and publication bias were evaluated.
RESULTS: Eighteen articles were included; 11 provided information on primary dentition and 15 on permanent dentition. Random-effects models showed a significant association between asthma and caries for both primary and permanent dentition, the odds ratios being 2.73 (95% CI: 1.61, 4.64) and 2.04 (95% CI: 1.44, 2.89), respectively.
CONCLUSIONS:Evidence from this analysis suggests that asthma doubles the risk of caries in both primary and permanent dentition. Publication bias diagnostics and simulation suggested possible overestimation of the summary odds ratio for permanent dentition but not for primary dentition. Physicians and dentists should recommend preventive measures against caries for people with asthma.
Evid Based Dent. 2012;13(2):41. doi: 10.1038/sj.ebd.6400854.
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儿童期哮喘的流行病学检测:横断面和纵向表现的一致性
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2001-2010年间美国哮喘发病率、卫生保健使用和死亡率趋势