月经前哮喘和症状与月经前综合征有关
2010/12/17
摘要
背景：目前，月经前哮喘与月经前综合征的关系尚不清楚。本研究根据是否存在月经前哮喘，对哮喘女性的月经前综合征进行比较。
方法：针对育龄期哮喘女性，设计月经周期呼吸道症状及与月经前综合征相关症状的问卷调查。项目包括烦躁不安-精神症状（焦虑、抑郁、疲劳、易怒和情绪不稳定）、水肿症状（腹部和乳房胀、水肿、痤疮、偏头痛）及其他症状（脚痛、恶心、出汗、呕吐和倦怠）。收集早晨和晚上峰值流量评分以评价肺功能。经前哮喘定义为，根据呼吸道症状和/或峰值流量，排卵前的月经前阶段，哮喘客观恶化≥ 20%。症状变化强度根据效应量评价。
结果：103名育龄期女性入选，46名女性（44.7%）存在月经前哮喘。排卵前的月经前阶段，所有症状均增加，这些症状增加在存在月经前哮喘的女性中更为明显，特别是腹胀 (效应量：0.88与0.33; p =0.009)和乳房胀(0.95 和0.49; p = .018)。
结论：月经前哮喘与月经前烦躁不安症状恶化，及某些水肿症状（如腹胀和乳房胀及水肿感）相关。
（林江涛 审校）
J Asthma. 2010 Oct;47(8):835-840.
Premenstrual asthma and symptoms related to premenstrual syndrome.
Pereira-Vega A, Sánchez JL, Gil FL, Maldonado JA, Bravo JM, Ignacio JM, Vázquez R, Álvarez F, Romero P, Sánchez I.
Pneumology Section, Hospital Juan Ramón Jiménez, Huelva, Spain. apv01h@saludalia.com
Abstract
BACKGROUND: It is unclear whether premenstrual asthma is associated with premenstrual syndrome. The objective of this study is to compare premenstrual symptoms among asthmatic women according to whether they have premenstrual asthma or not.
METHODS: A questionnaire on respiratory symptoms during a single menstrual cycle was developed for asthmatics of fertile age, together with another on symptoms related to premenstrual syndrome. These included dysphoric-psychiatric symptoms (anxiety, depression, fatigue, irritability, and mood swings), edematous symptoms (abdominal and mammary tension, swelling, acne, and migraine), and other symptoms (leg pains, nausea, sweating, vomiting, and tiredness). Morning and evening peak flow scores were collected to evaluate lung function. Premenstrual asthma was determined to be a ≥ 20% objective exacerbation in the premenstrual phase over the preovulatory phase in terms of both respiratory symptoms and/or peak flow. The intensity of the change in symptoms was evaluated according to the effect size.
RESULTS: The study examined 103 patients of fertile age, 46 of whom (44.7%) presented with premenstrual asthma. Practically all of the monitored symptoms increased in the premenstrual phase with respect to the preovulatory phase. This increase was greater in women with premenstrual asthma, especially for abdominal tension (effect size .88 against .33; p = .009) and mammary tension (.95 against .49; p = .018).
CONCLUSIONS: A clear link was found between premenstrual asthma and the premenstrual exacerbation of dysphoric symptoms, and certain edematous symptoms such as abdominal and mammary tension as well as a swelling sensation.
J Asthma. 2010 Oct;47(8):835-40.
背景：目前，月经前哮喘与月经前综合征的关系尚不清楚。本研究根据是否存在月经前哮喘，对哮喘女性的月经前综合征进行比较。
方法：针对育龄期哮喘女性，设计月经周期呼吸道症状及与月经前综合征相关症状的问卷调查。项目包括烦躁不安-精神症状（焦虑、抑郁、疲劳、易怒和情绪不稳定）、水肿症状（腹部和乳房胀、水肿、痤疮、偏头痛）及其他症状（脚痛、恶心、出汗、呕吐和倦怠）。收集早晨和晚上峰值流量评分以评价肺功能。经前哮喘定义为，根据呼吸道症状和/或峰值流量，排卵前的月经前阶段，哮喘客观恶化≥ 20%。症状变化强度根据效应量评价。
结果：103名育龄期女性入选，46名女性（44.7%）存在月经前哮喘。排卵前的月经前阶段，所有症状均增加，这些症状增加在存在月经前哮喘的女性中更为明显，特别是腹胀 (效应量：0.88与0.33; p =0.009)和乳房胀(0.95 和0.49; p = .018)。
结论：月经前哮喘与月经前烦躁不安症状恶化，及某些水肿症状（如腹胀和乳房胀及水肿感）相关。
（林江涛 审校）
J Asthma. 2010 Oct;47(8):835-840.
Premenstrual asthma and symptoms related to premenstrual syndrome.
Pereira-Vega A, Sánchez JL, Gil FL, Maldonado JA, Bravo JM, Ignacio JM, Vázquez R, Álvarez F, Romero P, Sánchez I.
Pneumology Section, Hospital Juan Ramón Jiménez, Huelva, Spain. apv01h@saludalia.com
Abstract
BACKGROUND: It is unclear whether premenstrual asthma is associated with premenstrual syndrome. The objective of this study is to compare premenstrual symptoms among asthmatic women according to whether they have premenstrual asthma or not.
METHODS: A questionnaire on respiratory symptoms during a single menstrual cycle was developed for asthmatics of fertile age, together with another on symptoms related to premenstrual syndrome. These included dysphoric-psychiatric symptoms (anxiety, depression, fatigue, irritability, and mood swings), edematous symptoms (abdominal and mammary tension, swelling, acne, and migraine), and other symptoms (leg pains, nausea, sweating, vomiting, and tiredness). Morning and evening peak flow scores were collected to evaluate lung function. Premenstrual asthma was determined to be a ≥ 20% objective exacerbation in the premenstrual phase over the preovulatory phase in terms of both respiratory symptoms and/or peak flow. The intensity of the change in symptoms was evaluated according to the effect size.
RESULTS: The study examined 103 patients of fertile age, 46 of whom (44.7%) presented with premenstrual asthma. Practically all of the monitored symptoms increased in the premenstrual phase with respect to the preovulatory phase. This increase was greater in women with premenstrual asthma, especially for abdominal tension (effect size .88 against .33; p = .009) and mammary tension (.95 against .49; p = .018).
CONCLUSIONS: A clear link was found between premenstrual asthma and the premenstrual exacerbation of dysphoric symptoms, and certain edematous symptoms such as abdominal and mammary tension as well as a swelling sensation.
J Asthma. 2010 Oct;47(8):835-40.
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