幼儿时期看电视时间与后期哮喘发病的相关性评估
2009/05/18
为研究是否幼儿时期看电视的时间与后期哮喘发病有关， Sherriff等人对参加Avon纵向亲子研究（ALSPAC）的无喘息症状的幼儿进行了前瞻性调查研究，随访从3.5～11.5岁。该研究以医生诊断的哮喘作为随访终点，包括在7.5岁有哮喘症状和/或之前12个月进行过哮喘治疗的11.5岁患儿。在入选的幼儿中，从39个月开始父母记录儿童每天看电视的时间。
这项前瞻性的纵向调查结果显示，从没有喘息症状的3.5岁幼儿随访至11.5岁时，哮喘的发病率仅6% (185/3065)。在3.5岁看电视时间增加的儿童，其11.5岁时哮喘的发病率也增加(p for linear trend = 0.0003)。每天看电视超过2小时的儿童其在11.5岁之后发生哮喘的发病率几乎是那些每天只看1～2小时电视的儿童的2倍(修正后似然比 1.8 (95% CI 1.2 to 2.6))。由此研究得出，在3.5岁没有喘息症状的幼儿长期看电视可能参与后期儿童时期哮喘的发生，两者之间存在相关性。
这项前瞻性的纵向调查结果显示，从没有喘息症状的3.5岁幼儿随访至11.5岁时，哮喘的发病率仅6% (185/3065)。在3.5岁看电视时间增加的儿童，其11.5岁时哮喘的发病率也增加(p for linear trend = 0.0003)。每天看电视超过2小时的儿童其在11.5岁之后发生哮喘的发病率几乎是那些每天只看1～2小时电视的儿童的2倍(修正后似然比 1.8 (95% CI 1.2 to 2.6))。由此研究得出，在3.5岁没有喘息症状的幼儿长期看电视可能参与后期儿童时期哮喘的发生，两者之间存在相关性。
（于娜 中国医科大学附属第一医院呼吸内科 110001 摘译）
（Thorax 2009;64:321-325 ）
Thorax 2009;64:321-325
Association of duration of television viewing in early childhood with the subsequent development of asthma
A Sherriff1, A Maitra2, A R Ness3, C Mattocks4, C Riddoch4, J J Reilly5, J Y Paton5 and A J Henderson6
Objective: To investigate whether duration of television (TV) viewing in young children is associated with subsequent development of asthma.
Methods: Children taking part in the Avon Longitudinal Study of Parents and Children (ALSPAC) with no wheeze up to the age of 3.5 years and follow-up data at 11.5 years of age took part in a prospective longitudinal cohort study. The main outcome measure was asthma, defined as doctor-diagnosed asthma by 7.5 years of age with symptoms and/or treatment in the previous 12 months at 11.5 years of age. Parental report of hours of TV viewing per day by the children was ascertained at 39 months.
Results: In children with no symptoms of wheeze at 3.5 years of age and follow-up data at 11.5 years of age, the prevalence of asthma was 6% (185/3065). Increased TV viewing at 3.5 years was associated with increased prevalence of asthma at 11.5 years of age (p for linear trend = 0.0003). Children who watched television for >2 h/day were almost twice as likely to develop asthma by 11.5 years of age as those watching TV for 1–2 h/day (adjusted odds ratio 1.8 (95% CI 1.2 to 2.6)).
Conclusion: Longer duration of TV viewing in children with no symptoms of wheeze at 3.5 years of age was associated with the development of asthma in later childhood.
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怀孕母亲膳食结构与儿童呼吸性和变应性疾病转归之间的关系
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水果摄入对儿童哮喘的影响
