水果摄入对儿童哮喘的影响
2009/05/18
关键词： 哮喘；儿童；饮食；水果
有观点认为大量进食水果可能降低哮喘的发病危险，为了验证这一假说，Fogarty对英国东部地区进行了一项自然研究，该地区自2003年6月起开始逐步实施学校水果计划。
2004年Fogarty对东部内陆地区接受1年免费水果的儿童和东部地区未接受免费水果的儿童进行问卷调查。共有4971例（53%）干预组儿童和5770例（54%）对照组儿童收回问卷。尽管干预组的水果消耗量明显高于对照组，但哮喘症状的严重性无明显差异，过去12个月中两组患者喘息症状的OR为1（95%CI，0.88–1.14）。
研究证实，免费水果餐不能对儿童哮喘的严重性产生直接影响，但这些数据也不足以推翻水果摄入改善哮喘控制的假说。
（韩伟 青岛市市立医院东院呼吸科 266071 摘译）
（Eur Respir J. 2009 Mar;33(3):481-485）
Eur Respir J. 2009 Mar;33(3):481-5
A natural experiment on the impact of fruit supplementation on asthma symptoms in children.
Fogarty AW, Antoniak M, Venn AJ, Davies L, Goodwin A, Salfield N, Britton JR, Lewis SA.
Keywords: Asthma, children, diet, fruit
A high fruit intake may reduce the risk of asthma. The English National School Fruit Scheme was introduced in the East Midlands region of the UK in June 2003 and in the Eastern region in September 2004. Questionnaires were distributed to children aged 4-6 yrs in schools in May 2003. This was repeated in May 2004 when those in the East Midlands had received free fruit for 1 yr and those in the Eastern region had not. Responses were obtained in 2004 for 4,971 (53%) and 5,770 (54%) children in the intervention and control regions, respectively. Despite an increase in fruit consumption in the intervention compared with the control region between 2003 and 2004, there was no difference between the two regions in the prevalence or severity of asthma symptoms after 1 yr of fruit supplementation (odds ratio for wheeze in the past 12 months in intervention compared with control region 1.00, 95% confidence interval 0.88-1.14). Providing free fruit at school for 1 yr does not have any immediate effect on prevalence or severity of asthma in young children, although these data do not refute the hypothesis that a higher increase in fruit intake improves measures of asthma control.
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幼儿时期看电视时间与后期哮喘发病的相关性评估
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学前儿童喘鸣的远期预后： 纵向邮寄问卷研究1993～2004.
