性别影响成年哮喘控制吗?
2014/05/08
摘要
几项研究表明哮喘的患病率存在性别差异,但几乎没有哮喘控制的相关信息。本研究旨在评估性别对成年哮喘控制的影响。对年龄超过18岁,定期赴过敏性专科随访的242例患者的病例进行评估。使用标准哮喘调查问卷类似哮喘控制试验(ACT)进行评估。根据性别,比较前一年ACT评分,临床特征和人口数据如吸烟状态,教育,哮喘持续时间、严重性,特异性,哮喘家族史,抗过敏性止痛药,急诊、住院人数。在该项研究中,77.3%的患者为女性。平均年龄、体重指数和哮喘持续时间分别为39.0 ± 0.7,27.3 ± 0.3和 6.6 ± 0.4年。总数的14.9%的患者为吸烟者,且55.8%的患者毕业于初中,22.7%毕业于高中,14%毕业于大学。特应性比率57%。在他们中有18.6%使用抗过敏性止痛剂。30.2%的患者有哮喘家族史。45.5%的患者为哮喘轻度、40.9%为中度,13.6%为重度。三分之一的患者入急诊科,前一年1/10的患者因哮喘住院治疗。ACT评分表明,67.8%的患者哮喘完全控制,17.8%的患者部分控制,14.5%的患者未控制。根据ACT评分和临床特征,比较男性、女性哮喘患者的结果,无显著的统计学差异。最后,结果证实,性别对使用标准调查问卷进行评估的成年哮喘控制无影响。
(林江涛 审校)
Chron Respir Dis. 2014 Mar 21. [Epub ahead of print]
Does gender affect asthma control in adult asthmatics?
Dursun AB1, Kar Kurt O, Bayiz H, Ozkan E, Cakaloglu A, Karasoy D.
ABSTRACT
Several studies have shown gender differences in prevalence of asthma but there is little information about asthma control. In this study, we aimed to evaluate the effect of gender on asthma control in adult asthmatics. Medical records of 242 patients older than 18 years of age who regularly visited the allergy unit were evaluated. Standardized asthma questionnaires like the asthma control test (ACT) were performed. ACT scores, clinical characteristics, and demographic data such as smoking status, education, duration and severity of asthma, atopic status, family history of asthma, analgesic hypersensitivity, number of emergency visits, and hospitalization in the previous year were compared based on gender. In this study, 77.3% of the patients were female. Mean age, body mass index, and duration of asthma were 39.0 ± 0.7, 27.3 ± 0.3, and 6.6 ± 0.4 years, respectively. Of the total, 14.9% of the patients were smokers. Also, 55.8% of them were graduated from middle school, 22.7% from high school, and 14% from university. Atopy rate was 57%. Analgesic hypersensitivity was found in 18.6% of them. There was 30.2% family history of asthma. The asthma severity was mild in 45.5%, moderate in 40.9%, and severe in 13.6% of the patients. One-third of the patients were admitted to emergency room; 1/10th were hospitalized due to asthma in the previous year. ACT scores indicated complete control in 67.8%, partial control in 17.8%, and uncontrolled asthma in 14.5%. Comparing the results of males with females having asthma, there was no statistically significant difference between the two gender according to ACT scores and clinical characteristics. Finally, the results conclude that there was no effect of gender on asthma control assessed with standardized questionnaire in adult asthmatics.
Chron Respir Dis. 2014 Mar 21. [Epub ahead of print]
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过敏原、致病菌和哮喘的关系
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