哮喘联盟

   摘要
   背景：当前美国成人哮喘患病率已经达到历史高水平。虽然国家水平的评估表明成人哮喘患病率从2000年～2009年增加了33%，但具体各州的当前哮喘患病率的时间趋势及其危险因素尚未被探究。
   方法：使用来自50个州以及哥伦比亚特区的2000年～2009年行为危险因素监测系统数据，以2年为一周期(2000～2001, 2002～2003, 2004～2005, 2006～2007, 2008～2009)评估具体各州的当前哮喘患病率。每个州均采用4个logistic回归模型评估随时间变化当前哮喘患病率是否有统计学上显著的线性改变，并解释了社会人口学因素、吸烟情况和体重情况(身体质量指数作为指标)与哮喘患病率的关系。
   结果：2000年～2009年期间，50个州以及哥伦比亚特区的当前哮喘患病率是增加的，其中92%(46/50)的州以及哥伦比亚特区显著增加。在校正了社会人口学因素模型中的体重情况和吸烟情况后， 10个先前显示显著增加的州(AR, AZ, IA, IL, KS, ME, MT, UT, WV, and WY)当前哮喘患病率并没有显著增加。
   结论:从2000年～2009年美国大多数州当前成人哮喘患病率有显著增加的趋势。某些州的肥胖患病率可能增加当前哮喘患病率。

（林江涛 审校）

BMC Public Health. 2013 Dec 10;13(1):1156. [Epub ahead of print]
 

Trends in adult current asthma prevalence and contributing risk factors in the United States by state: 2000--2009.

Zhang X, Morrison-Carpenter T, Holt JB, Callahan DB.

ABSTRACT
BACKGROUND: Current asthma prevalence among adults in the United States has reached historically high levels. Although national-level estimates indicate that asthma prevalence among adults increased by 33% from 2000 to 2009, state-specific temporal trends of current asthma prevalence and their contributing risk factors have not been explored.
METHODS: We used 2000--2009 Behavioral Risk Factor Surveillance System data from all 50 states and the District of Columbia (D.C.) to estimate state-specific current asthma prevalence by 2-year periods (2000--2001, 2002--2003, 2004--2005, 2006--2007, 2008--2009). We fitted a series of four logistic-regression models for each state to evaluate whether there was a statistically significant linear change in the current asthma prevalence over time, accounting for sociodemographic factors, smoking status, and weight status (using body mass index as the indicator).
RESULTS: During 2000--2009, current asthma prevalence increased in all 50 states and D.C., with significant increases in 46/50 (92%) states and D.C. After accounting for weight status in the model series with sociodemographic factors, and smoking status, 10 states (AR, AZ, IA, IL, KS, ME, MT, UT, WV, and WY) that had previously shown a significant increase did not show a significant increase in current asthma prevalence.
CONCLUSIONS: There was a significant increasing trend in state-specific current asthma prevalence among adults from 2000 to 2009 in most states in the United States. Obesity prevalence appears to contribute to increased current asthma prevalence in some states.
 

BMC Public Health. 2013 Dec 10;13(1):1156. [Epub ahead of print]