低健康认知力的老年人哮喘预后不佳
2013/12/04
摘要
目的:评价健康认知力(HL)与老年人哮喘预后间的相关性。
方法:本研究纳入了纽约和芝加哥的年龄≥60岁的中重度哮喘患者。采用哮喘控制问卷(ACQ)评估哮喘控制,呼吸量测定法预测1秒用力呼气量(FEV1)百分比,过去6个月里住院治疗以及急诊室(ED)的访问次数,以及生活质量评估。采用成人健康认知功能简短试验(S-TOFHLA)评估HL。多因素logistic回归分析模型控制年龄、性别、种族、收入、总体健康状况和哮喘患病年数。
结果:433例患者中,36%为低HL,55%年龄超过65岁,38%为西班牙裔,22%为黑人。结果报告40%的患者哮喘控制不佳,32%FEV1 < 70%预计值;9%有过一次住院治疗,23%有过一次急诊室治疗,38%生活质量差。经多因素分析,低HL患者更可能发生FEV1 < 70%预计值(比值比 [OR] 2.34, 95% 置信区间[CI] 1.39-3.94, p=0.001)、因哮喘导致的住院治疗(OR 2.53, 95% CI 1.17-5.49, p=0.02)和急诊室治疗(OR 1.81, 95% CI 1.05-3.10, p=0.03)。患者自述的哮喘控制与生活质量无差异。
结论:低HL与客观评估的哮喘控制不佳、更高的急诊室治疗和住院概率相关。HL是一个可改善老年人哮喘结果的可控干预目标。
(林江涛 审校)
J Asthma. 2013 Oct 8. [Epub ahead of print]
Asthma Outcomes Are Poor among Older Adults with Low Health Literacy.
Federman AD, Wolf MS, Sofianou A, O'Conor R, Martynenko M, Halm EA, Leventhal H, Wisnivesky JP.
Abstract
ABSTRACT OBJECTIVE: To examine the association of health literacy (HL) with asthma outcomes among older asthmatics.
METHODS: The study included adults ages ≥60 with moderate to severe asthma in New York City and Chicago. We assessed asthma control with the Asthma Control Questionnaire (ACQ) and the percent predicted forced expiratory volume at 1 second (FEV1) by spirometry, hospitalizations and emergency department (ED) visits in the past 6 months, and quality of life. HL was assessed with the Short Test of Functional Health Literacy in Adults (S-TOFHLA). Multivariate logistic regression models controlled for age, sex, race, income, general health, and years with asthma.
RESULTS: Among 433 individuals, 36% had low HL, 55% were over age 65, 38% were Hispanic, and 22% were black. Poor asthma control was reported by 40% and 32% had FEV1 < 70% of predicted; 9% had a hospital stay, 23% had an ED, and 38% had poor quality of life. In multivariable analysis, individuals with low HL were more likely to have FEV1 < 70% predicted (odds ratio [OR] 2.34, 95% confidence interval [CI] 1.39-3.94, p=0.001), hospitalizations (OR 2.53, 95% CI 1.17-5.49, p=0.02) and ED visits for asthma (OR 1.81, 95% CI 1.05-3.10, p=0.03). There were no differences in self-reported asthma control and quality of life.
CONCLUSIONS:Low HL is associated with poor asthma control by objective measure, and greater likelihood of ED visits and hospitalization. HL is a modifiable target for interventions to improve asthma outcomes in the elderly.
J Asthma. 2013 Oct 8. [Epub ahead of print]
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确定肺功能加速下降哮喘患者特征表型的聚类分析研究
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通过高分辨率电子计算机断层扫描(HRCT)评估轻度间歇性哮喘患者的气道壁厚度