一项将个体和电话辅导相结合进行戒烟的多中心随机试验
2013/11/13
摘要
目标：该研究评估了个体和电话辅导相结合的戒烟计划与单纯个体辅导或电话辅导戒烟计划相比的有效性。
方法：一项随机、多中心、开放标签试验，于2009年1月～2011年7月在西班牙6个戒烟门诊开展实施。在772例评估符合条件的吸烟者中，600例（77%）达到入组标准并随机分配。吸烟者随机分配到接受个体辅导组、联合电话和个体辅导组和电话辅导组。主要终点为52周时经生化确认的持续戒烟。
结果：电话辅导组52周戒烟率明显低于联合组（20.1% vs. 29.0%; OR, 1.32; 95% CI, 1.1-2.7）和个体辅导组（20.1% vs. 27.9%; OR, 1.37; 95% CI, 1.0-2.8）。联合组52周戒烟率未明显高于个体组（OR, 0.97; 95% CI, 0.7-1.4）。
结论：相比单独电话辅导，个体咨询以及联合个体、电话辅导52周戒烟率较高。联合方法可能在临床吸烟治疗中非常有用，因为此法较单独个体辅导减少了就诊次数，从而降低了计划成本，而且此法相比单独电话咨询提高了患者依从性。
（刘国梁 审校）
Prev Med. 2013 Sep;57(3):183-8. doi: 10.1016/j.ypmed.2013.05.014. Epub 2013 Jun 1.
A multicentre randomized trial of combined individual and telephone counselling for smoking cessation.
Ramon JM, Nerin I, Comino A, Pinet C, Abella F, Carreras JM, Banque M, Baena A, Morchon S, Jimenez-Muro A, Marqueta A, Vilarasau A, Bullon R, Masuet-Aumatell C.
ABSTRACT
OBJECTIVE: The present study assessed the effectiveness of smoking cessation programs combining individual and telephone counselling, compared to individual or telephone counselling alone.
METHOD: A randomized, multicentre, open-label trial was performed between January 2009 and July 2011 at six smoking cessation clinics in Spain. Of 772 smokers assessed for eligibility, 600 (77%) met inclusion criteria and were randomized. Smokers were randomized to receive individual counselling, combined telephone and individual counselling, or telephone counselling. The primary outcome was biochemically validated continuous abstinence at 52weeks.
RESULTS: The 52-week abstinence rate was significantly lower in the telephone group compared to the combined group (20.1% vs. 29.0%; OR, 1.32; 95% CI, 1.1-2.7) and to the individual counselling group (20.1% vs. 27.9%; OR, 1.37; 95% CI, 1.0-2.8). The 52-week abstinence rates were not significantly higher in the combined group than the individual group (OR, 0.97; 95% CI, 0.7-1.4).
CONCLUSION: Individual counselling and combined individual and telephone counselling were associated with higher 52-week abstinence rates than telephone counselling alone. A combined approach may be highly useful in the clinical treatment of smokers, as it involves less clinic visits than individual counselling alone, thus reducing the program cost, and it increases patient compliance compared to telephone counselling alone.
Prev Med. 2013 Sep;57(3):183-8. doi: 10.1016/j.ypmed.2013.05.014. Epub 2013 Jun 1.
