哮喘联盟

   摘要
   背景：尽管全球哮喘和头痛发病率均较高，但是对两者之间的联系知之甚少。本研究的目的是在韩国人群中评估哮喘和日常头痛的关系。
   方法：分别对7,984例参与第二次韩国全国健康和营养调查(KNHANES II)的受试者进行分析，这是2001年由卫生和福利部组织的一项前瞻性管理性调查。
   结果：7,984例受试者中，69例(0.9%)患有每日头痛，429例(5.4%)有哮喘症状。每日头痛伴有哮喘症状者(14/429, 3.3%)较无症状者(55/7555, 0.7%; P<0.001)更为常见。4,833例非吸烟者中，46例(1.0%)患每日头痛，287例(5.9%)有哮喘症状，每日头痛伴哮喘症状者(11/231, 4.8%)较无症状者(35/4602, 0.8%; P<0.001)更为常见。多因素回归分析显示，所有有哮喘症状的受试者患每日头痛的比值比是2.3 (95% CI: 1.21-4.33, P=0.01) ，有哮喘症状的非吸烟者是3.4 (95% CI: 1.65-7.12, P=0.001)。
   结论：有症状哮喘患者较无症状哮喘患者罹患日常头痛风险更高，提示两者之间有关联性。
 

（刘国梁 审校）
J Asthma. 2013 May 7. [Epub ahead of print]


 

Is Daily Headache Related to Asthma? Results from a population-based survey.
 

Seok Lee Y, Dong Lee G, Seung Lee J, Kook Rhee C, Sun Shim T, Sung Kim W, Lee SD, Oh YM.

Abstract
ABSTRACT BACKGROUND: Despite the high worldwide prevalence of asthma and headache, little is known about the association between these conditions. The objective of our study was to evaluate the association between asthma and daily headache in a representative sample of the general population of South Korea.
METHODS: We retrospectively analyzed 7,984 individuals included in the Second Korean National Health and Nutrition Examination Survey (KNHANES II), a prospectively administered survey performed in 2001 by a government organization within the Ministry of Health and Welfare. After adjustment of risk factors for daily headache, multivariate logistic regression analysis was performed to evaluate the association between asthma and daily headache.
RESULTS: Of 7,984 individuals, 69 (0.9%) had daily headache and 429 (5.4%) had asthma symptoms.Daily headache was significantly more prevalent in subjects with asthma symptoms (14/429, 3.3%) than in those without (55/7555, 0.7%; P<0.001). Of the 4,833 nonsmokers, 46 (1.0%) had daily headache and 287 (5.9%) had asthma symptoms, with daily headache being significantly more prevalent in subjects with asthma symptoms (11/231, 4.8%) than in those without (35/4602, 0.8%; P<0.001). Multivariate logistic regression showed that the odds ratios for daily headache were 2.3 (95% CI: 1.21-4.33, P=0.01) in all individuals with asthma symptoms and 3.4 (95% CI: 1.65-7.12, P=0.001) in nonsmokers with asthma symptoms.
CONCLUSION: Individuals with asthma symptoms are at higher risk of daily headache than those without the symptoms, suggesting a link between these conditions.

J Asthma. 2013 May 7. [Epub ahead of print]