哮喘联盟

   摘要
   目的：评估无家可归的吸烟者使用尼古丁贴片时附加的动机式访谈(MI)对戒烟的影响。
   设计：两组、随机、对照试验，随访26周。
   受试者和背景：来自美国明尼苏达州明尼阿波利斯/圣保罗市紧急收容所和过渡居所的430名无家可归吸烟者参与本研究。
   干预和措施：所有受试者接受21mg尼古丁贴片持续8周治疗。干预组受试者接受6周个体化的MI建议，增强受试者戒烟的动机和对对尼古丁贴片的依从性。标准治疗对照组受试者接受一次关于戒烟的建议。主要终点为第26周后7日戒烟率，用呼出气一氧化碳浓度和唾液中的可替宁水平判断。
   结果：意向治疗分析证实，26周后干预组7日戒烟率相比对照组没有显著升高(9.3% vs 5.6%, P = 0.15)。未戒烟的受试者之中，两组26周后吸烟量与基线相比的下降值基本相同(MI： -13.7 ± 11.9 vs 标准治疗：-13.5 ± 16.2)。
   结论：对无家可归吸烟者26周的随访发现，使用尼古丁贴片时增加动机访谈咨询并未显著增加吸烟率。

 

（林江涛 审校）
Addiction. 2013 Jun;108(6):1136-44. doi: 10.1111/add.12140. Epub 2013 Mar 19.
 

Motivational interviewing to enhance nicotine patch treatment for smoking cessation among homeless smokers: a randomized controlled trial.
 

Okuyemi KS, Goldade K, Whembolua GL, Thomas JL, Eischen S, Sewali B, Guo H, Connett JE, Grant J, Ahluwalia JS, Resnicow K, Owen G, Gelberg L, Des Jarlais D.

Abstract
AIMS: To assess the effects of adding motivational interviewing (MI) counseling to nicotine patch for smoking cessation among homeless smokers.
DESIGN: Two-group randomized controlled trial with 26-week follow-up.
PARTICIPANTS AND SETTING: A total of 430 homeless smokers from emergency shelters and transitional housing units in Minneapolis/St Paul, Minnesota, USA.
INTERVENTION AND MEASUREMENTS: All participants received 8-week treatment of 21-mg nicotine patch. In addition, participants in the intervention group received six individual sessions of MI counseling which aimed to increase adherence to nicotine patches and to motivate cessation. Participants in the standard care control group received one session of brief advice to quit smoking.Primary outcome was 7-day abstinence from cigarette smoking at 26 weeks, as validated by exhaled carbon monoxide and salivary cotinine.
FINDINGS: Using intention-to-treat analysis, verified 7-day abstinence rate at week 26 for the intervention group was non-significantly higher than for the control group (9.3% versus 5.6%, P = 0.15). Among participants who did not quit smoking, reduction in number of cigarettes from baseline to week 26 was equally high in both study groups (-13.7 ± 11.9 for MI versus -13.5 ± 16.2 for standard care).
CONCLUSIONS: Adding motivational interviewing counseling to nicotine patch did not increase smoking rate significantly at 26-week follow-up for homeless smokers.
 

Addiction. 2013 Jun;108(6):1136-44. doi: 10.1111/add.12140. Epub 2013 Mar 19.