哮喘成人患者的焦虑敏感性、哮喘控制和生活质量
2012/02/29
方法:将评价心理症状和哮喘症状的自我检测指标,通过社区“过敏症和哮喘”办公室邮寄给368名哮喘患者自我症状报告表,这些患者在2009年1月1日和2010年1月1日间接受医生的随访。参与本研究的患者包括127名哮喘患者(74%为女性,平均年龄为43.4岁,SD=12.3),完成并回寄这些自我报告指标。
结果:经性别、年龄、负面影响和共患病数校正后,AS的躯体因素能显著预测哮喘控制和哮喘相关生活质量的各个部分(症状、活动受限、情绪功能和环境刺激)。
结论:这些结果对前期的结果进行了延伸,显示身体感觉的恐惧对哮喘控制和生活质量能产生负面影响。这些结果也同时表明,针对AS躯体因素的采取措施,可能是改善哮喘控制和生活质量的新方法。
J Asthma. 2012 Feb;49(1):57-62. Epub 2011 Dec 16.
Department of Psychology, University of Cincinnati , Cincinnati, OH , USA.
OBJECTIVE:The aim of this study was to examine the role of anxiety sensitivity (AS) in terms of asthma control and asthma-related quality of life in a sample of adults with a physician-verified diagnosis of asthma.
METHODS:Self-report measures assessing psychological and asthma symptoms were mailed to 368 asthma patients from a community allergy and asthma office who had been seen for a physician follow-up visit between 1 January 2009 and 1 January 2010. Participants in the current study were 127 asthma patients (74% female; M(age) = 43.4 years, SD = 12.3) who completed and returned the self-report measures.
RESULTS:The results indicated that, after controlling for gender, age, negative affect, and number of comorbid medical problems, the physical concerns factor of AS (AS-Physical Concerns) significantly predicted asthma control and all domains of asthma-related quality of life (symptoms, activity limitations, emotional functioning, and environmental stimuli).
CONCLUSIONS:These findings replicate and extend previous research and indicate that the fear of physical sensations negatively affects both asthma control and quality of life. These findings also suggest that targeting the AS-Physical Concerns may be a novel way to improve asthma control and quality of life.
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评价国家心脏、肺和血液研究所指南中各个评估指标对哮喘控制分类和预测哮喘发作的作用
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为期26周的随机、双盲、安慰剂对照、多中心研究,评价奥玛珠单抗对持续过敏性哮喘患者哮喘控制的影响