日本成人哮喘患病率的时间趋势:基于来自日本藤枝市1985、1999和2006年人群调查结果
2011/07/06
摘要
背景:哮喘负担是目前很重要的公共卫生问题。大部分国家,哮喘的发病率在过去几十年内呈现增加趋势。然而,近期的流行病学研究显示,在一些发达国家,自上世纪90年代后,哮喘的患病率趋于平稳,或者甚至呈现下降趋势。但有关日本成人哮喘发病率的时间趋势尚不清楚。
方法:于1985、1999和2006年,在日本静冈藤枝市进行了3次人群调查,这些结果在以前的研究中已进行了报道。本研究对前述三次的流行病学调查结果进行比较分析,以解释成人哮喘发病率的时间趋势。虽然三次调查所采用的问卷调查不一样,但是时间趋势可通过比较不同问卷调查间对相关问题的反应来评价。
结果:从1985~1999年,普通感冒后的喘息和夜间呼吸困难感呈现显著增加趋势(分别为4.2%至7.6%和 3.2%至5.3%)。从1999~2006年,终身哮喘和当前哮喘的患病率呈现显著增加趋势(分别为5.1%至6.7%, 和1.5%至3.4%)。
结论:藤枝市成人哮喘的患病率从1985年至2006年呈现一致的增加趋势。没有证据显示,患病率呈现平台期或下降。我们的结果提示,有必要阻断哮喘患病率的增加,以减轻日本社会的负担。
(刘国梁 审校)
Allergol Int. 2011 May 25. [Epub ahead of print]
Time Trend in the Prevalence of Adult Asthma in Japan: Findings from Population-Based Surveys in Fujieda City in 1985, 1999, and 2006.
Fukutomi Y, Taniguchi M, Watanabe J, Nakamura H, Komase Y, Ohta K, Akasawa A, Nakagawa T, Miyamoto T, Akiyama K.
Source
Clinical Research Center for Allergy and Rheumatology, Sagamihara National Hospital, Kanagawa, Japan.
Abstract
BACKGROUND: The burden of asthma is recognized as an important public health problem worldwide. In most countries, the prevalence of asthma has been reported to increase in the last few decades. However, more recent epidemiological studies have shown that the prevalence of asthma has been flat or even decreasing after the 1990s in some developed countries. The recent time trend in the prevalence of adult asthma in Japan is unknown.
METHODS: Population-based surveys were conducted three times in the same region, in 1985, 1999, and 2006, at Fujieda City, Shizuoka, Japan, and the results were reported previously. We compared the results of these surveys to reveal the time trend in the prevalence of adult asthma. Although the questionnaires used in these surveys were not exactly the same, the time trend was assessed by comparing the responses to relevant questions between questionnaires.
RESULTS: The prevalences of wheeze following a common cold and dyspneal feeling at night increased significantly from 1985 to 1999 (4.2% to 7.6%, and 3.2% to 5.3%, respectively). The prevalences of lifetime asthma and current asthma also significantly increased from 1999 to 2006 (5.1% to 6.7%, and 1.5% to 3.4%, respectively).
CONCLUSIONS: The prevalences of asthma among adults in Fujieda City consistently increased from 1985 to 2006. There was no evidence that the prevalences were in plateau or decreasing. These findings suggest that more efforts are required to stop the increase in the burden of this disease in Japan.
Allergol Int. 2011 May 25. [Epub ahead of print]
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肥胖和哮喘:经哮喘发病年龄校正后的相关性
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美国国立卫生研究院/美国国家心脏,肺和血液研究所进行的严重哮喘研究项目,通过聚类分析,证实儿童严重哮