哮喘与ABO血型无关
2009/11/17
在输血和移植中，ABO血型是最为重要的血型系统。糖基转移酶受ABO系统调节，有助于红细胞和血管内皮细胞细胞表面及外分泌系统（包括呼吸道）寡糖结构的形成。本文在200名哮喘儿童和成人及2000名健康人群中分析ABO血型系统。哮喘患者和健康人群中最常见的血型是“O”（分别为43.5%和43.6%），其次是“B”，“A”和“AB”。至于血型的分布在两组人群中未见显著差异（P= 0.931）。
因此，我们认为，在迈索尔、卡纳塔克邦和南印度人群中，ABO血型系统与哮喘无关。
（苏楠 审校）
Lung. 2009 Sep 22. [Epub ahead of print]
Lack of Association Between Asthma and ABO Blood Group.
Bijanzadeh M, Ramachandra NB, Mahesh PA, Savitha MR, Manjunath BS, Jayaraj BS.
Human Genetics Laboratory, Department of Studies in Zoology, University of Mysore, Manasagangothri, Mysore, 570 006, India.
ABO is the most important blood group system in transfusion and transplantation practices. Glycosyltransferases are controlled by the ABO system which is helpful in building oligosaccharide structures on the cell surface of erythrocytes and vascular endothelium and in the exocrine secretion system, including the respiratory tract. We analyzed the ABO blood group of 200 children and adults with asthma as well as that of 2000 healthy subjects as controls. The most common blood group among the patients and controls was "O" (43.5% and 43.6%, respectively), followed by B, A, and AB. In the distribution of different blood groups, nonsignificant difference between patients and controls was observed (p = 0.931). We conclude that ABO blood group status has a nonsignificant association with asthma among the population of Mysore, Karnataka, South India.
Lung. 2009 Sep 22. [Epub ahead of print]
因此，我们认为，在迈索尔、卡纳塔克邦和南印度人群中，ABO血型系统与哮喘无关。
（苏楠 审校）
Lung. 2009 Sep 22. [Epub ahead of print]
Lack of Association Between Asthma and ABO Blood Group.
Bijanzadeh M, Ramachandra NB, Mahesh PA, Savitha MR, Manjunath BS, Jayaraj BS.
Human Genetics Laboratory, Department of Studies in Zoology, University of Mysore, Manasagangothri, Mysore, 570 006, India.
ABO is the most important blood group system in transfusion and transplantation practices. Glycosyltransferases are controlled by the ABO system which is helpful in building oligosaccharide structures on the cell surface of erythrocytes and vascular endothelium and in the exocrine secretion system, including the respiratory tract. We analyzed the ABO blood group of 200 children and adults with asthma as well as that of 2000 healthy subjects as controls. The most common blood group among the patients and controls was "O" (43.5% and 43.6%, respectively), followed by B, A, and AB. In the distribution of different blood groups, nonsignificant difference between patients and controls was observed (p = 0.931). We conclude that ABO blood group status has a nonsignificant association with asthma among the population of Mysore, Karnataka, South India.
Lung. 2009 Sep 22. [Epub ahead of print]
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美国儿童和青少年肥胖与哮喘的关系
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