哮喘控制与医疗资源使用、工作能力丧失和健康相关生活质量的关系

2009/09/16

    目的:确定哮喘控制与健康预后之间的关系。
    方法:对来源于2006年美国全国卫生与健康调查的哮喘患者数据进行横断面研究。采用哮喘控制调查表检测哮喘控制。相关预后包括工作能力的丧失/活动受限、健康相关生活质量以及医疗资源使用。哮喘控制对预后的影响采用线性和Poisson回归模型分析。
    结果:共纳入2767名哮喘未得到有效控制的患者和2912名哮喘有效控制的患者。校正混杂因素后,哮喘控制患者的健康相关生活质量调查表(SF-8)中的体力和精神评分明显增加(P < 0.001);而且哮喘控制患者急诊就诊次数下降、住院天数减少、医生家庭随访次数下降,工作能力丧失/活动受限也得到明显改善。
    结论:结果显示,哮喘控制与较好的健康预后有关。采用适当的治疗来改善哮喘控制水平能有效减少与哮喘相关的直接和间接医疗支出。
 
(苏楠 审校)
Williams SA, Wagner S, Kannan H, et al.
 J Occup Environ Med. 2009 Jul;51(7):780-5.
 
 
The association between asthma control and health care utilization, work productivity loss and health-related quality of life.
 
Williams SA, Wagner S, Kannan H, Bolge SC.
 
Health Economics and Outcomes Research, AstraZeneca LP, Wilmington, DE, USA.
OBJECTIVE: To determine the association between asthma control and health outcomes.
METHODS: Cross-sectional data on asthmatic patients were from the 2006 U.S. National Health and Wellness Survey. Asthma control was determined by the Asthma Control Test. Outcomes assessed included work productivity loss/activity impairment, health-related quality of life, and resource utilization. Effects of asthma control on outcomes were determined with linear and Poisson regression models.
RESULTS: There were 2767 uncontrolled asthmatics and 2912 controlled asthmatics. Adjusting for confounders, controlled asthmatics reported (P < 0.001) higher physical and mental health-related quality of life scores (SF-8); fewer emergency room visits, hospitalization days, and medical provider visits; lower levels of overall work productivity loss and activity impairment.
CONCLUSION: Results indicate that asthma control is associated with better health outcomes. Management with therapies optimizing asthma control may reduce direct and indirect costs of treatment.


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