哮喘的经济负担：系统综述
2009/07/09
背景：哮喘治疗常产生巨大的治疗费用，其中包括直接和间接的开支。此外，哮喘的发生及其引起的死亡也会导致未来潜在的收入下降。本文主要研究与哮喘相关的经济负担。
方法：于MEDLINE，EMBASE，PUBMED，CINAHL，CDSR，OHE-HEED及科学数据库网站检索1966～2008年的相关文献。
结果：68项研究满足本研究要求。住院和药物治疗是哮喘相关直接费用的主要支出。失业和失学在导致哮喘间接费用增加的原因中所占比例最大。哮喘相关费用与共患疾病、年龄和疾病严重程度相关。
结论：尽管已有有效的预防性治疗措施，但与哮喘相关的费用仍在上升。包括对患者和医生进行宣教和定期随访在内的干预措施有助于降低哮喘患者的经济负担。
（林江涛 审校）
BMC Pulm Med. 2009 May 19;9(1):24. [Epub ahead of print]
Economic burden of asthma: a systematic review.
Bahadori K, Doyle-Waters MM, Marra C, Lynd L, Alasaly K, Swiston J, Fitzgerald JM.
ABSTRACT:
ABSTRACT:
BACKGROUND: Asthma is associated with enormous healthcare expenditures that include both direct and indirect costs. It is also associated with the loss of future potential earnings related to both morbidity and mortality. The objective of the study is to determine the burden of disease costs associated with asthma.
METHODS: We performed a systematic search of MEDLINE, EMBASE, PUBMED, CINAHL, CDSR, OHE-HEED, and Web of Science Databases between 1966 and 2008.
RESULTS: Sixty-eight studies met the inclusion criteria. Hospitalization and medications were found to be the most important cost driver of direct costs. Work and school loss accounted for the greatest percentage of indirect costs. The cost of asthma was correlated with comorbidities, age, and disease severity.
CONCLUSIONS: Despite the availability of effective preventive therapy, costs associated with asthma are increasing. Strategies including education of patients and physicians and regular follow-up are required to reduce the economic burden of asthma.
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