哮喘联盟

    背景：本研究与体育锻炼假说有关，旨在探讨体育锻炼和看电视对发展中国家青少年哮喘和过敏性鼻炎的影响，这些地区往往缺乏公众的运动场所。
    方法：对马其顿共和国斯科普里地区3026名13/14岁青少年进行问卷调查，（问卷来源于standardized International Study of Asthma and Allergies in Childhood Phase Three此段不知如何翻译，请教儿科医师），将一定强度体育锻炼和电视观看时间作为变量对获得的数据进行logistic回归分析(OR，95％CI)，探讨二者对青少年哮喘和过敏性鼻炎的影响。
    结果：“每星期1～2次和³3次”的一定强度体育锻炼可加重目前的哮喘症状，并增加其他类型喘息症状发生的风险（例如限制说话程度的喘息和运动诱发的喘息）。经常的体育锻炼只与目前的过敏性鼻炎症状正相关(aOR: 1.40; 1.04-1.90; P = 0.029)。每天观看电视“≥ 3小时会增加目前喘息症状(aOR: 1.34; 1.01-1.77; P = 0.042)和运动诱发哮喘(aOR: 1.32; 1.05-1.65; P = 0.016)发生的风险。
    结论：该发现证实了传统观点，即久坐和体质欠佳可加重哮喘症状而非过敏性鼻炎。同时发现体质欠佳和哮喘没有控制时进行体育锻炼可能会诱发哮喘发作。

（陈欣 审校）
Vlaski E, et al. Allergol Immunopathol (Madr). 2008 Sep-Oct;36(5):247-253.

Allergol Immunopathol (Madr).2008 Sep-Oct;36(5):247-53. Links

Influence of physical activity and television-watching time on asthma and allergic rhinitis among young adolescents: preventive or aggravating?

Vlaski E, Stavric K, Seckova L, Kimovska M, Isjanovska R.

Department of Pulmonology and Allergology. University Children’s Hospital. Skopje. The Republic of Macedonia. vlaskie@sonet.com.mk.

BACKGROUND: Related to exercise hypothesis, the aim of the present study was to explore the influence of physical activity on asthma and allergic rhinitis in a developing country where publicity campaigns about the benefits of exercise are scarce. 
METHODS: The analysed data were self-reported and obtained through the standardized International Study of Asthma and Allergies in Childhood Phase Three written questionnaires completed by 3026 adolescents 13/14 year old in Skopje (Republic of Macedonia). Vigorous physical activity and television-watching time both unadjusted and adjusted for confounding factors were used as variables for analysis. Odds ratios (OR, 95 % CI) in binary logistic regression were employed for statistic analysis of the data.
RESULTS: Vigorous physical activity both >/= 3 times and 1-2 times per week was associated with an increased risk of current wheeze (aOR: 1.66; 1.08-2.55; p = 0.020 and aOR: 1.70; 1.23-2.36; p = 0.001, respectively), speech-limiting wheeze (aOR: 3.15; 1.13-8.77; p = 0.028 and aOR: 4.62; 2.22-9.62; p = 0.000, respectively) and exercise-induced wheeze (aOR: 2.72; 1.93-3.83; p = 0.000 and aOR: 4.01; 3.12-5.14; p = 0.000, respectively). Frequent physical activity was positively associated only with current allergic rhinitis symptoms (aOR: 1.40; 1.04-1.90; p = 0.029). Television watching >/= 3 hours a day increased the risk of current wheeze (aOR: 1.34; 1.01-1.77; p = 0.042) and exercise-induced wheeze (aOR: 1.32; 1.05-1.65; p = 0.016).
CONCLUSION: The findings support the aggravating role of sedentary regimen and poor physical fitness on asthma symptoms, but not on allergic rhinitis. Physical activity may trigger asthma symptoms when physical fitness is poor and asthma is not controlled.