吸烟对表皮的作用
2009/07/30
目的：文章回顾了吸烟对皮肤和其附属物的影响。
方法：这篇文章的文献回顾是建立在MEDLINE(1966～2004)的研究上。文章应用了英语和MeSH术语，如表皮、皮肤病学、烟草、皮肤、吸烟。另一项附加关于吸烟引起的疾病的相关研究随后开始，这项研究重点在于发病学和流行病学。提供的最高证明水平和最新的报道的文献最先被选择。
结论：吸烟对表皮的影响是非常有害的，在提供专业的观点教育公众及宣传吸烟对皮肤的有害作用方面，皮肤科医生将起到很大的作用。
方法：这篇文章的文献回顾是建立在MEDLINE(1966～2004)的研究上。文章应用了英语和MeSH术语，如表皮、皮肤病学、烟草、皮肤、吸烟。另一项附加关于吸烟引起的疾病的相关研究随后开始，这项研究重点在于发病学和流行病学。提供的最高证明水平和最新的报道的文献最先被选择。
结论：吸烟对表皮的影响是非常有害的，在提供专业的观点教育公众及宣传吸烟对皮肤的有害作用方面，皮肤科医生将起到很大的作用。
（孙力超编译 刘国梁审校）
J Cutan Med Surg. 2004 Nov-Dec;8(6):415-423
Cutaneous effects of smoking.
Freiman A, Bird G, Metelitsa AI, Barankin B, Lauzon GJ.
Division of Dermatology, McGill University, Montreal, Quebec, Canada. anatoli.freiman@sympatico.ca
J Cutan Med Surg. 2004 Nov-Dec;8(6):415-23
BACKGROUND: Cigarette smoking is the single biggest preventable cause of death and disability in developed countries and is a significant public health concern. While known to be strongly associated with a number of cardiovascular and pulmonary diseases and cancers, smoking also leads to a variety of cutaneous manifestations. OBJECTIVE: This article reviews the effects of cigarette smoking on the skin and its appendages.
METHODS: A literature review was based on a MEDLINE search (1966-2004) for English-language articles using the MeSH terms cutaneous, dermatology, tobacco, skin, and smoking. An additional search was subsequently undertaken for articles related to smoking and associated mucocutanous diseases, with the focus on pathogenesis and epidemiologic data. Articles presenting the highest level of evidence and latest reports were preferentially selected.
RESULTS: Smoking is strongly associated with numerous dermatologic conditions including poor wound healing, wrinkling and premature skin aging, squamous cell carcinoma, psoriasis, hidradenitis suppurativa, hair loss, oral cancers, and other oral conditions. In addition, it has an impact on the skin lesions observed in diabetes, lupus, and AIDS. The evidence linking smoking and melanoma, eczema, and acne is inconclusive. Anecdotal data exist on the possible protective effects of smoking in oral/genital aphthosis of Behçet’s disease, herpes labialis, pyoderma gangrenosum, acral melanoma, and Kaposi’s sarcoma in AIDS patients.
CONCLUSIONS: An appreciation of the adverse cutaneous consequences of smoking is important. Dermatologists can play an integral role in promoting smoking cessation by providing expert opinion and educating the public on the deleterious effects of smoking on the skin.
PMID: 15988548 [PubMed - indexed for MEDLINE]
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在暴露于过敏原的小鼠中，环境中烟草烟雾暴露不会降低糖皮质激素减轻炎症、重构和气道高反应的作用
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