吸烟对心血管系统的影响
2009/07/30
吸烟后烟草中的毒性成分通过循环系统分布到人体整个机体。尼古丁、一氧化碳、自由基和细胞因子都可以影响到循环系统。这些毒性成分可以导致动脉粥样硬化斑块的形成以及斑块的不稳定性。因此，吸烟已成为冠心病、心源性猝死、缺血性脑卒中、主动脉瘤形成、外周血管病和血栓闭塞性脉管炎的最重要的独立危险因素。而吸烟这种心血管危险因素是完全可以通过人为去除的。
流行病学调查证实的资料INTERHEART研究显示了在白天和夜间吸烟的数量与冠心病事件发作之间有着很强的依存性。为了降低这些心血管事件风险我们必须动员所有的预防措施以保护每个人远离吸烟及成瘾。而于现在的烟草成瘾依赖者来说，应当及时予以行为治疗或者使用科学方法证实有效的药物治疗以戒除烟草毒害。
流行病学调查证实的资料INTERHEART研究显示了在白天和夜间吸烟的数量与冠心病事件发作之间有着很强的依存性。为了降低这些心血管事件风险我们必须动员所有的预防措施以保护每个人远离吸烟及成瘾。而于现在的烟草成瘾依赖者来说，应当及时予以行为治疗或者使用科学方法证实有效的药物治疗以戒除烟草毒害。
（张永明编译 刘国梁审校）
Curr Vasc Pharmacol. 2004 Apr;2(2):175-182
The effects of smoking on cardiovascular system
Nikodemowicz M.
nikodemowicz@vp.pl
Smoking is a very popular habit of inhaling tobacco smoke. Toxic components of the tobacco smoke are being distributed throughout the whole organism by means of circulation. Nicotine, carbon monoxide, free radicals and cytokines fundamentally influence circulation. These components cause creation of atherosclerotic plaque and its destabilization. These processes make smoking the most important single risk factor in coronary artery disease, sudden cardiac death, ischemic stroke, aortic aneurysm formation, peripheral vascular disease and Buerger disease. It must be also said this factor might be possibly removed. Epidemiologic examinations confirm that The INTERHEART study showed strongly growing dependence between the number of cigarettes smoked during the day and night and the risk of coronary heart attack. In order to lower the risk we should mobilize all preventive actions which would protect us from smoking and addiction. But for those who are already chain smokers we should apply behavior therapy or eventually use drugs which are scientifically proved to be effective.
PMID: 18540324 [PubMed - indexed for MEDLINE]
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