环境烟草暴露与儿童行为的关系
2009/05/18
理论依据：有证据显示，环境烟草暴露与儿童行为问题存在联系，但是以往的研究主要来自家长自述的暴露情况而没有决定性的结果。
目的：为了调查环境烟草暴露与哮喘儿童行为之间的关系。
方法：该研究纳入了220例哮喘患儿，通过尼古丁代谢产物可替宁的血清浓度检测评估烟草暴露情况，以及家长应用儿童行为评估系统报告患儿的行为问题。多因素校正分析包括：性别、年龄、种族、哮喘严重程度、哮喘药物、母亲的教育、出生前的烟草暴露、母亲的消极情绪、以及环境积分的测量的家庭观察数据。
结果：哮喘女童可替宁浓度较高，可替宁浓度与行为改变之间不存在关联。哮喘男童的可替宁浓度较低，但是与行为改变之间存在一定的关系：烟草暴露越多，哮喘男童越可能出现外在的行为问题，如活动过度、具有攻击性和行为异常，同时也越可能出现内在行为问题，如焦虑和沮丧等。
结论：哮喘儿童环境烟草暴露与男童的行为问题增加有关系。
（苏楠 卫生部中日友好医院呼吸内科 100029 摘译 ）
J Dev Behav Pediatr.2008 Dec;29(6):450-457. Links
J Dev Behav Pediatr.2008 Dec;29(6):450-7. Links
Environmental tobacco smoke exposure and child behaviors.
Yolton K, Khoury J, Hornung R, Dietrich K, Succop P, Lanphear B.
Department of Pediatrics, Division of General and Community Pediatrics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229-3039, USA. kimberly.yolton@cchmc.org
RATIONALE: Emerging evidence suggests that exposure to environmental tobacco smoke (ETS) may be linked with behavior problems in childhood, but previous research has relied primarily on parent report of exposure, and results are inconclusive.
OBJECTIVES: To investigate the relationship between exposure to ETS and child behavior problems among children with asthma.
METHODS: The sample included 220 children who were enrolled in an asthma intervention trial and regularly exposed to ETS at home. Serum cotinine was used to measure exposure to tobacco smoke, and behavior problems were assessed by parent report on the Behavior Assessment System for Children. Covariates in adjusted analyses included: sex, age, race, asthma severity, asthma medication, maternal education, prenatal tobacco exposure, maternal depression, and Home Observation for Measurement of the Environment score.
RESULTS: Child behavior problems increased with increasing exposure to ETS. A stratified analysis of boys and girls separately indicated higher exposure among girls, but behavior problems were statistically significantly associated with exposure only in boys. Increasing behavior problems included externalizing behavior problems (beta= 2.23, p =.02) such as hyperactivity and aggression, internalizing behavior problems (beta= 2.19, p= .01) such as depression, and behavior symptoms (beta= 2.55, p= .01).
CONCLUSIONS: Among children with asthma, exposure to ETS is related to increased child behavior problems among boys.
PMID: 19093323 [PubMed - indexed for MEDLINE]
目的：为了调查环境烟草暴露与哮喘儿童行为之间的关系。
方法：该研究纳入了220例哮喘患儿，通过尼古丁代谢产物可替宁的血清浓度检测评估烟草暴露情况，以及家长应用儿童行为评估系统报告患儿的行为问题。多因素校正分析包括：性别、年龄、种族、哮喘严重程度、哮喘药物、母亲的教育、出生前的烟草暴露、母亲的消极情绪、以及环境积分的测量的家庭观察数据。
结果：哮喘女童可替宁浓度较高，可替宁浓度与行为改变之间不存在关联。哮喘男童的可替宁浓度较低，但是与行为改变之间存在一定的关系：烟草暴露越多，哮喘男童越可能出现外在的行为问题，如活动过度、具有攻击性和行为异常，同时也越可能出现内在行为问题，如焦虑和沮丧等。
结论：哮喘儿童环境烟草暴露与男童的行为问题增加有关系。
（苏楠 卫生部中日友好医院呼吸内科 100029 摘译 ）
J Dev Behav Pediatr.2008 Dec;29(6):450-457. Links
J Dev Behav Pediatr.2008 Dec;29(6):450-7. Links
Environmental tobacco smoke exposure and child behaviors.
Yolton K, Khoury J, Hornung R, Dietrich K, Succop P, Lanphear B.
Department of Pediatrics, Division of General and Community Pediatrics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229-3039, USA. kimberly.yolton@cchmc.org
RATIONALE: Emerging evidence suggests that exposure to environmental tobacco smoke (ETS) may be linked with behavior problems in childhood, but previous research has relied primarily on parent report of exposure, and results are inconclusive.
OBJECTIVES: To investigate the relationship between exposure to ETS and child behavior problems among children with asthma.
METHODS: The sample included 220 children who were enrolled in an asthma intervention trial and regularly exposed to ETS at home. Serum cotinine was used to measure exposure to tobacco smoke, and behavior problems were assessed by parent report on the Behavior Assessment System for Children. Covariates in adjusted analyses included: sex, age, race, asthma severity, asthma medication, maternal education, prenatal tobacco exposure, maternal depression, and Home Observation for Measurement of the Environment score.
RESULTS: Child behavior problems increased with increasing exposure to ETS. A stratified analysis of boys and girls separately indicated higher exposure among girls, but behavior problems were statistically significantly associated with exposure only in boys. Increasing behavior problems included externalizing behavior problems (beta= 2.23, p =.02) such as hyperactivity and aggression, internalizing behavior problems (beta= 2.19, p= .01) such as depression, and behavior symptoms (beta= 2.55, p= .01).
CONCLUSIONS: Among children with asthma, exposure to ETS is related to increased child behavior problems among boys.
PMID: 19093323 [PubMed - indexed for MEDLINE]
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