过敏性疾病和哮喘的经济影响—HEAD泛欧登记系统
2025/06/27
摘要
过敏性疾病的卫生经济学（HEAD）登记系统是一个基于欧洲的登记系统，由欧洲过敏和临床免疫学学会与各国过敏学会合作开发，以促进标准化的过敏性疾病管理。这是第一项基于登记系统的研究，采用观察性设计，在来自四个国家（比利时、意大利、罗马尼亚和西班牙）的778名过敏性鼻炎、哮喘、特应性皮炎和食物过敏的成人和儿童中，描述了过敏性疾病的治疗模式及其对医疗系统（诊断和管理成本）、社会（误工作/上学天数和残疾津贴/支持）和患者（自付费用）的影响。每例患者和每年的平均总费用为1329.55±1947.39欧元，间接费用为338.68±1629.61欧元。直接费用包括：住院费用82.74±585.90欧元，急诊科费用17.50±125.07欧元，专科医生费用172.94±323.17欧元，初级保健费用22.70±132.42欧元，心理医生费用4.85±136.84欧元，诊断费用21.24±82.47欧元，治疗费用104.81±469.26欧元。间接成本分别为医疗费（16.24±106.40）欧元、药费（161.90±710.58）欧元、交通费（44.15±218.51）欧元、私人保险（16.77±157.91）欧元、避让（8.65±92.99）欧元和环境控制（99.33±955.23）欧元。成年人工作日损失（1.02±3.20）天，儿童工作日损失（0.53±2.18）天，家庭损失（1.38±13.83）天。各国在管理模式和费用方面存在高度异质性。过敏性疾病的巨大负担要求立即采取行动以更好地管理。
Economic Impact of Allergic Diseases and Asthma-The HEAD Pan-European Registry
Ioana Agache, Maria Torres, Ibon Eguiluz-Gracia, Elena Bradatan, Kamal El Abd, Maria Beatrice Bilo, Federica Rivolta, Andrea Sangalli, Roxana Bumbacea, Selda Ali, Dario Antolin, Águeda Concepción Lario Cuenda, Vicente Albéndiz, Maria Miguel Oliveira, Paulo Jorge Nogueira, Loreto Carmona; HEAD Study Group
Abstract
The Health Economics of Allergic Diseases (HEAD) registry is a European-based registry developed by the European Academy of Allergy and Clinical Immunology in collaboration with national allergy societies to facilitate standardised allergic disease management. Using an observational design, this first registry-based study describes care patterns for allergic diseases and their impact on the healthcare system (diagnostic and management costs), society (missed work/school days and disability pension/support) and patients (out-of-pocket costs) in 778 adults and children with allergic rhinitis, asthma, atopic dermatitis and food allergy, from four countries (Belgium, Italy, Romania and Spain). The average total costs per patient and per year were €1329.55 ± 1947.39, with indirect costs of €338.68 ± 1629.61. Direct costs consisted of €82.74 ± 585.90 for hospitalisations, €17.50 ± 125.07 for the emergency department, €172.94 ± 323.17 for specialists, €22.70 ± 132.42 for primary care, €4.85 ± 136.84 for psychologists, €21.24 ± 82.47 for diagnosis and €104.81 ± 469.26 for treatments. Indirect costs were out-of-pocket consultation fees (€16.24 ± 106.40), medications (€161.90 ± 710.58), transportation (€44.15 ± 218.51), private insurance (€16.77 ± 157.91), avoidance (€8.65 ± 92.99) and environmental control (€99.33 ± 955.23). Adults missed 1.02 ± 3.20 workdays, children missed 0.53 ± 2.18 schooldays and burdened their families with 1.38 ± 13.83 lost days. There was a high degree of heterogeneity across countries for management patterns and for costs. The significant burden of allergic diseases calls for immediate action for better management.
过敏性疾病的卫生经济学（HEAD）登记系统是一个基于欧洲的登记系统，由欧洲过敏和临床免疫学学会与各国过敏学会合作开发，以促进标准化的过敏性疾病管理。这是第一项基于登记系统的研究，采用观察性设计，在来自四个国家（比利时、意大利、罗马尼亚和西班牙）的778名过敏性鼻炎、哮喘、特应性皮炎和食物过敏的成人和儿童中，描述了过敏性疾病的治疗模式及其对医疗系统（诊断和管理成本）、社会（误工作/上学天数和残疾津贴/支持）和患者（自付费用）的影响。每例患者和每年的平均总费用为1329.55±1947.39欧元，间接费用为338.68±1629.61欧元。直接费用包括：住院费用82.74±585.90欧元，急诊科费用17.50±125.07欧元，专科医生费用172.94±323.17欧元，初级保健费用22.70±132.42欧元，心理医生费用4.85±136.84欧元，诊断费用21.24±82.47欧元，治疗费用104.81±469.26欧元。间接成本分别为医疗费（16.24±106.40）欧元、药费（161.90±710.58）欧元、交通费（44.15±218.51）欧元、私人保险（16.77±157.91）欧元、避让（8.65±92.99）欧元和环境控制（99.33±955.23）欧元。成年人工作日损失（1.02±3.20）天，儿童工作日损失（0.53±2.18）天，家庭损失（1.38±13.83）天。各国在管理模式和费用方面存在高度异质性。过敏性疾病的巨大负担要求立即采取行动以更好地管理。
(中日友好医院呼吸与危重症医学科 顾宪民 摘译 林江涛 审校)
（Allergy. 2025 May 20. doi: 10.1111/all.16596.）
Economic Impact of Allergic Diseases and Asthma-The HEAD Pan-European Registry
Ioana Agache, Maria Torres, Ibon Eguiluz-Gracia, Elena Bradatan, Kamal El Abd, Maria Beatrice Bilo, Federica Rivolta, Andrea Sangalli, Roxana Bumbacea, Selda Ali, Dario Antolin, Águeda Concepción Lario Cuenda, Vicente Albéndiz, Maria Miguel Oliveira, Paulo Jorge Nogueira, Loreto Carmona; HEAD Study Group
Abstract
The Health Economics of Allergic Diseases (HEAD) registry is a European-based registry developed by the European Academy of Allergy and Clinical Immunology in collaboration with national allergy societies to facilitate standardised allergic disease management. Using an observational design, this first registry-based study describes care patterns for allergic diseases and their impact on the healthcare system (diagnostic and management costs), society (missed work/school days and disability pension/support) and patients (out-of-pocket costs) in 778 adults and children with allergic rhinitis, asthma, atopic dermatitis and food allergy, from four countries (Belgium, Italy, Romania and Spain). The average total costs per patient and per year were €1329.55 ± 1947.39, with indirect costs of €338.68 ± 1629.61. Direct costs consisted of €82.74 ± 585.90 for hospitalisations, €17.50 ± 125.07 for the emergency department, €172.94 ± 323.17 for specialists, €22.70 ± 132.42 for primary care, €4.85 ± 136.84 for psychologists, €21.24 ± 82.47 for diagnosis and €104.81 ± 469.26 for treatments. Indirect costs were out-of-pocket consultation fees (€16.24 ± 106.40), medications (€161.90 ± 710.58), transportation (€44.15 ± 218.51), private insurance (€16.77 ± 157.91), avoidance (€8.65 ± 92.99) and environmental control (€99.33 ± 955.23). Adults missed 1.02 ± 3.20 workdays, children missed 0.53 ± 2.18 schooldays and burdened their families with 1.38 ± 13.83 lost days. There was a high degree of heterogeneity across countries for management patterns and for costs. The significant burden of allergic diseases calls for immediate action for better management.
上一篇：
青少年暴露于苯并酮类紫外线吸收剂：与肥胖、心脏代谢生物标志物及哮喘/过敏之间的横断面关联——基于六项欧洲生物监测研究
下一篇：
代谢型与未控制儿童哮喘、肠道微生物群和全身炎症相关性研究
