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2008年至2016年瑞典西部哮喘患病率和呼吸系统症状的变化

2019/05/10

   摘要
   背景:哮喘是常见的气道慢性炎症性疾病,在20世纪后半叶患病率明显增加。最近评估成人患病率趋势的研究是不一致的。我们调查了瑞典西部2008年至2016年间哮喘患病率,呼吸系统症状和危险因素的变化。
   方法:瑞典西部哮喘研究(WSAS)是一项基于人群的研究,始于2008年(WSAS I),然后于2016年在瑞典西部重复(WSAS II)。随机选择年龄在16-75岁的人(2008年N = 18087,2016年N = 24534)完成了关于阻塞性肺病,呼吸系统症状,潜在危险因素以及GA2 LEN调查问题的调查问卷。
   结果:2008年至2016年期间,报告的哮喘发病率,医生诊断哮喘,使用哮喘药物和当前哮喘的患病率分别从9.6%上升到11%,8.3%到10%,8.6%到9.8%,8.1%到9.1%。在同一时期,呼吸道症状的患病率也有所增加。增幅最大的是年龄在16-25岁的年轻人。与2008年一样,女性,过敏性鼻炎,肥胖和哮喘家族史在2016年仍然是哮喘最严重的危险因素。
   结论:瑞典西部地区的成人哮喘和呼吸系统症状在2008年至2016年间有中度增加,年轻人增加最多。在研究期间,哮喘的潜在危险因素保持不变。

 
(中日友好医院呼吸与危重症医学科 王瑞茵 摘译 林江涛 审校)
(Allergy. 2019 Apr 25. doi: 10.1111/all.13840. [Epub ahead of print])

 
 
 
Changes in the prevalence of asthma and respiratory symptoms in western Sweden between 2008 and 2016.
 
Borna E, Nwaru BI, Bjerg A, Mincheva R, Rådinger M, Lundbäck B, Ekerljung L.
 
Abstract
BACKGROUND:Asthma is a common chronic inflammatory disease of the airways, with a noticeable increase in prevalence during the second half of the 20th century. Recent studies assessing the prevalence trends among adults have been inconsistent. We investigated the changes in the prevalence of asthma, respiratory symptoms and risk factors between 2008 and 2016 in western Sweden.
METHODS:The West Sweden Asthma Study (WSAS) is a population-based study which started in 2008 (WSAS I) and then repeated in 2016 (WSAS II) in western Sweden. Randomly selected individuals aged 16-75 years (N=18087 in 2008 and N=24534 in 2016) completed a questionnaire regarding obstructive lung diseases, respiratory symptoms, potential risk factors and also questions from the GA2 LEN survey.
RESULTS:The prevalence of reported ever asthma, physician diagnosed asthma, use of asthma medication, and current asthma increased significantly from 9.6% to 11%, 8.3% to 10%, 8.6% to 9.8%, and 8.1% to 9.1% respectively, between 2008 and 2016. There were also increases in the prevalence of respiratory symptoms during the same period. The greatest increase occurred in young adults aged 16-25 years. Female gender, allergic rhinitis, obesity and family history of asthma remained the strongest risk factors for asthma in 2016 as it was in 2008.
CONCLUSIONS:There were moderate increases in asthma and respiratory symptoms in adults in western Sweden between 2008 and 2016, the greatest increase occurring in younger adults. The potential risk factors for asthma remained the same during the study period. This article is protected by copyright. All rights reserved.




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