电子烟安全性评估及其与心血管疾病的关系
2018/01/15
摘要
吸烟导致多种疾病的生成和发展。更为重要的是，吸烟室导致冠心病独立危险因素。近些年，电子烟已经成为传统吸烟替代方法，而现代微电子技术也为模拟传统吸烟提供了可能。此外，电子烟既简单有时髦。然而，关于电子烟的安全性仍有颇多争议。尽管关于电子烟的研究不断增多，但并没有关于安全性的系统性研究。本研究旨在综述现有关于电子烟安全性的报道，并充分了解其危害和缺点。研究发现大多数现有研究为短期和体外研究。仅有少数是体内或长期研究。值得注意的是，电子烟中的有害成分浓度，例如可挥发有机物，烟草特异性氮氨酶和重金属甚至高于传统烟草。因此，电子烟是否能够作为安全合适的替代方法仍需进一步研究。
Safety Assessment of Electronic Cigarettes and Their Relationship with Cardiovascular Disease.
Int J Environ Res Public Health. 2018 Jan 5;15(1). pii: E75. doi: 10.3390/ijerph15010075.
Zhang G, Wang Z, Zhang K, Hou R, Xing C, Yu Q, Liu E.
Abstract
Smoking leads to the occurrence and development of a variety of diseases. Most importantly, it is an independent risk factor of cardiovascular atherosclerosis. In recent years, electronic cigarettes have become a popular alternative to traditional cigarettes, since modern micro-electronic techniques provide the possibility of simulating the process of traditional smoking. Additionally, it is convenient and fashionable. Nevertheless, comments about the safety of electronic cigarettes remain controversial. Although the research about electronic cigarettes increased exponentially, there has been no systematic study of its safety. The aim of the current study is to review the literature reports about the safety of electronic cigarettes, and to understand their hazards and disadvantages. It was found that most of the current research about electronic cigarettes comprises short-term and in vitro studies. There are few reports of in vivo and long-term studies. Notably, the level of harmful components such as volatile organic compounds, tobacco-specific nitrosamines and heavy metals in electronic cigarettes are even higher than in traditional cigarettes. Therefore, the harm of electronic cigarettes should not be underestimated. In conclusion, the question of whether electronic cigarettes are a safe and sufficient substitute for traditional smoking needs further investigation.
吸烟导致多种疾病的生成和发展。更为重要的是，吸烟室导致冠心病独立危险因素。近些年，电子烟已经成为传统吸烟替代方法，而现代微电子技术也为模拟传统吸烟提供了可能。此外，电子烟既简单有时髦。然而，关于电子烟的安全性仍有颇多争议。尽管关于电子烟的研究不断增多，但并没有关于安全性的系统性研究。本研究旨在综述现有关于电子烟安全性的报道，并充分了解其危害和缺点。研究发现大多数现有研究为短期和体外研究。仅有少数是体内或长期研究。值得注意的是，电子烟中的有害成分浓度，例如可挥发有机物，烟草特异性氮氨酶和重金属甚至高于传统烟草。因此，电子烟是否能够作为安全合适的替代方法仍需进一步研究。
（上海交通大学医学院附属瑞金医院呼吸与危重症医学科 周剑平 万欢英 摘译）
（Int J Environ Res Public Health. 2018 Jan 5;15(1). pii: E75. doi: 10.3390/ijerph15010075.）
（Int J Environ Res Public Health. 2018 Jan 5;15(1). pii: E75. doi: 10.3390/ijerph15010075.）
Safety Assessment of Electronic Cigarettes and Their Relationship with Cardiovascular Disease.
Int J Environ Res Public Health. 2018 Jan 5;15(1). pii: E75. doi: 10.3390/ijerph15010075.
Zhang G, Wang Z, Zhang K, Hou R, Xing C, Yu Q, Liu E.
Abstract
Smoking leads to the occurrence and development of a variety of diseases. Most importantly, it is an independent risk factor of cardiovascular atherosclerosis. In recent years, electronic cigarettes have become a popular alternative to traditional cigarettes, since modern micro-electronic techniques provide the possibility of simulating the process of traditional smoking. Additionally, it is convenient and fashionable. Nevertheless, comments about the safety of electronic cigarettes remain controversial. Although the research about electronic cigarettes increased exponentially, there has been no systematic study of its safety. The aim of the current study is to review the literature reports about the safety of electronic cigarettes, and to understand their hazards and disadvantages. It was found that most of the current research about electronic cigarettes comprises short-term and in vitro studies. There are few reports of in vivo and long-term studies. Notably, the level of harmful components such as volatile organic compounds, tobacco-specific nitrosamines and heavy metals in electronic cigarettes are even higher than in traditional cigarettes. Therefore, the harm of electronic cigarettes should not be underestimated. In conclusion, the question of whether electronic cigarettes are a safe and sufficient substitute for traditional smoking needs further investigation.
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