青少年哮喘在风险健康和肥胖的关系中的性别差异
2016/11/09
摘要
目的：评估青少年女生和男生健康与肥胖对哮喘风险的关系。
研究设计：使用1999-2004年全国健康和营养检查调查数据对12-19岁的参与者做了一个横断面评估。参加者完成心肺功能测试、身体成分测量，以及呼吸问卷调查。
结果：总共有4828名参与者被包括在内。超重/肥胖在女孩中与具有哮喘史（aOR 1.63，95% CI 1.16-2.30）、当前哮喘（aOR 1.73，95% CI 1.13，2.64）和喘息（aOR 1.40，95% CI 1.03-1.91）的比例增加有关。超重/肥胖在女孩中也与哮喘发作（aOR 2.67，95% CI 1.56-4.65）和运动喘息（aOR 1.60，95% CI 1.07-2.38）的风险增加相关。在男孩中，身体健康程度较高与哮喘急诊（aOR 0.24，95% CI 0.07-0.89）、喘息相关就医（aOR 0.31，95% CI 0.13-0.75）、喘息相关的请假（aOR 0.14，95% CI 0.06-0.33）以及运动相关的喘息（aOR 0.43，95% CI 0.24-0.76）的较低发生几率有关。
结论：在女孩而不是男孩中，超重/肥胖与哮喘的患病率和发病率有关，与是否健身无关。在男孩但不在女孩中，健康度较高与降低哮喘发病率有关，与体重状态无关。肥胖和健康在女孩与男孩中可能以不同的方式单独影响哮喘的发病和严重程度。
关键词：青少年；哮喘；健康；肥胖
（杨冬 审校）
1JPediatr.2016 Sep;176:36-42.doi:10.1016/j.jpeds.2016.05.050. Epub 2016 Jun 16.
Sex Differences in the Relationship between Fitness and Obesity on Risk for Asthma in Adolescents.
Lu KD1, Billimek J2, Bar-Yoseph R3, Radom-Aizik S3, Cooper DM3, Anton-Culver H4.
Author information
Abstract
OBJECTIVE:To evaluate the relationship of fitness and obesity on asthma risk in adolescent girls and boys.
STUDY DESIGN:A cross-sectional assessment of participants 12-19 years of age was conducted by the use of data from the 1999-2004 National Health and Nutrition Examination Survey. Participants completed cardiorespiratory fitness testing, body composition measurements, and respiratory questionnaires.
RESULTS:A total of 4828 participants were included. Overweight/obesity was associated with increased odds of history of asthma (aOR 1.63, 95% CI 1.16-2.30), current asthma (aOR 1.73, 95% CI 1.13, 2.64), and wheezing (aOR 1.40, 95% CI 1.03-1.91) in girls. Overweight/obesity also was associated with increased odds of asthma attacks (aOR 2.67, 95% CI 1.56-4.65) and wheezing related to exercise (aOR 1.60, 95% CI 1.07-2.38) in girls. High fitness was associated with lower odds of asthma-related visits to the emergency department (aOR 0.24, 95% CI 0.07-0.89), wheezing-related medical visits (aOR 0.31, 95% CI 0.13-0.75), wheezing-related missed days (aOR 0.14, 95% CI 0.06-0.33), and wheezing related to exercise (aOR 0.43, 95% CI 0.24-0.76) in boys.
CONCLUSION:Overweight/obesity is associated with increased asthma prevalence and morbidity in girls but not in boys, independent of fitness. High fitness is associated with decreased rates of asthma morbidity in boys but not in girls, independent of weight status. Obesity and fitness may each influence asthma onset and severity in different ways for girls compared with boys.
Copyright © 2016 Elsevier Inc. All rights reserved.
KEYWORDS:adolescents; asthma; fitness; obesity
1JPediatr.2016 Sep;176:36-42.doi:10.1016/j.jpeds.2016.05.050. Epub 2016 Jun 16.
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哮喘-慢性阻塞性肺疾病重叠综合征与肺栓塞危险之间的关系
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高中生吸烟、哮喘与相关的信念：一项以人群为基础的研究
