韩国高中生使用电子香烟与哮喘的关系
2016/05/26
摘要
目的：尽管电子香烟（EC）日益普及，但它们对健康的影响知之甚少。本研究的目的是探讨使用电子香烟与哮喘的关系。
方法：本研究是一个横断面研究。总共有35,904名高中生被列入研究人群。学生们患哮喘是基于学生自述的医生过去12个月的哮喘诊断。
结果：哮喘患者在 “目前吸电子烟”（N = 2,513），“以前吸电子烟”（N = 2,078），和“从没吸电子烟”（N = 31,313）人群中的患病率分别为3.9%（n = 98）、2.2%（n = 46）和1.7%（n = 530）。比较“目前吸电子烟”和“从没吸电子烟”哮喘患者，未经调整的比值比（OR）为2.36（95%可信区间：1.89-2.94）。为了控制传统香烟（CC）的影响，对受试者进行传统香烟吸食的分层（从没吸过传统香烟，以前吸过传统香烟，和正在吸食传统香烟）。在“从没吸过传统香烟”组，“目前吸电子烟”发生哮喘的的未经调整的OR为3.41（95%可信区间：1.79-6.49），调整之后的OR为2.74（95%可信区间：1.30-5.78）。通过由于哮喘症状导致的缺课天数来反映哮喘的严重性； 与“从未吸电子烟”组相比，“正在吸食电子烟”组中严重哮喘的患病率具有最高的调整OR。
结论：与韩国高中生参考群体比较，电子烟使用者与哮喘患病具有更高的相关性，并更可能导致由于严重的哮喘症状而缺课。总之，研究结果表明使用电子烟可能是哮喘的危险因素。该研究结果对建立一个科学基础的来评估吸食电子烟所带来的潜在的健康危害是有价值的。
（苏欣 审校）
PLoSOne. 2016 Mar 4;11(3):e0151022.doi:10.1371/journal.pone.0151022.eCollection 2016.
Association between Electronic Cigarette Use and Asthma among High School Students in South Korea.
Cho JH1, Paik SY2.
Author information
Abstract
OBJECTIVES:Little is known about health outcomes related to electronic cigarette (EC) use, despite its growing popularity. The aim of this study is to investigate the association between EC use and asthma.
METHODS:The study design is a cross-sectional study. A total of 35,904 high school students were included as the final study population. The presence of asthma was based on a student's self-reported doctor diagnosis of asthma in the past 12 months.
RESULTS:Prevalence rates of asthmatics in 'current EC users' (n = 2,513), 'former EC users' (n = 2,078), and 'never EC users' (n = 31,313), were 3.9% (n = 98), 2.2% (n = 46) and 1.7% (n = 530), respectively. Comparing 'current EC' users with 'never EC' users, the unadjusted OR for asthmawas 2.36 (95% CI: 1.89-2.94). In order to control for the effect of conventional cigarette (CC) smoking, after stratifying the subjects by the three CC smoking categories (never CC, former CC, and current CC), within the 'never CC' category, the unadjusted OR for asthma for 'current EC' users was 3.41 (95% CI: 1.79-6.49), and the adjusted OR was 2.74 (95% CI: 1.30-5.78). Severe asthma was reflected by the number of days absent from school due to asthma symptoms; current EC users had the highest adjusted OR for severe asthma compared to 'never EC' users.
CONCLUSIONS:When compared to a reference population of high school students in South Korea, EC users have an increased association withasthma and are more likely to have had days absent from school due to severe asthma symptoms. In conclusion, the results indicate that EC use may be a risk factor for asthma. The results may be useful in developing a scientific basis for the evaluation of a potential health hazard by EC.
PLoS One. 2016 Mar 4;11(3):e0151022. doi: 10.1371/journal.pone.0151022. eCollection 2016.
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中国哮喘危险因素中的环境与遗传易感性现状
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非裔美国女性的邻居和个人社会经济地位与哮喘发生率
