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青少年和青年人中抑郁和焦虑症状与哮喘和食物过敏的条件特殊性关联

2016/01/14

   摘要
   目的:
本研究在调查了14到21岁的青少年中,患有哮喘和食物过敏与抑郁和焦虑症状之间是否存在条件特殊关联性。
   方法:4972例青少年的数据来自于Mater大学的妊娠研究项目。抑郁和焦虑症状的评估采用青少年自评和青年自评
   结果:在青少年中发现了哮喘和抑郁的条件特殊关联,OR=1.37 [1.12, 1.67] ,以及食物过敏与焦虑的的条件特殊关联,OR=1.26 [1.04, 1.76] ,但是青年人中没有发现。然而哮喘与改善的抑郁症相关,OR=1.70 [1.13, 2.55],食物过敏与持续性焦虑相关,OR=1.26 [1.01, 1.59].
   结论:在青少年中,哮喘与抑郁症临床症状的风险增加相关,而食物过敏与焦虑临床症状的风险增加相关。未来的研究需要明确这些关系的方向和解释这些关系的机制。卫生专业人员应当了解患有哮喘或食物过敏的青少年中心理疾病风险的增加。


 

(杨冬 审校)
J Asthma. 2015 Nov 5:1-26. [Epub ahead of print]


 

 

Condition-Specific Associations of Symptoms of Depression and Anxiety in Adolescents and Young Adults with Asthma and Food Allergy.
 

Ferro MA1,2,3, Van Lieshout RJ1,3, Scott JG4,5, Alati R6,7, Mamun AA6, Dingle K8.
 

Abstract
OBJECTIVE:
This study examined associations of asthma and food allergy with symptoms of depression and anxiety at 14 and 21 years of age to determine whether condition-specific associations exist.
METHODS:Data come from 4972 adolescents in the Mater University Study of Pregnancy. Symptoms of depression and anxiety were assessed using the Youth Self-Report and Young Adult Self-Report.
RESULTS:Condition-specific associations between asthma and depression, OR=1.37 [1.12, 1.67] and between food allergy and anxiety, OR=1.26 [1.04, 1.76] were found during adolescence, but not in young adulthood. Whereas asthma was associated with resolved depression, OR=1.70 [1.13, 2.55], food allergy was associated with persistent anxiety, OR=1.26 [1.01, 1.59].
CONCLUSIONS:In adolescents, asthma is associated with an increased risk of clinically relevant symptoms of depression and food allergy with and increased risk of clinically relevant symptoms of anxiety. Future research is needed to clarify directionality and mechanisms explaining these relationships. Health professionals should be aware of the increased risk of mental health problems in adolescents with asthma or food allergy.

 

J Asthma. 2015 Nov 5:1-26. [Epub ahead of print]


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