哮喘联盟

   摘要
   引言：许多研究已经证明，室外污染可能加剧呼吸道症状和儿童哮喘。我们的目的是评估哮喘和室内外污染之间的关系。
   方法：在2012年5月至6月期间，我们对六所黎巴嫩学校12～19岁的学童进行了调查。该调查将国际儿童哮喘和过敏反应研究（ISAAC）的标准化调查问卷与其它室内外暴露的问题进行了结合。
   结果：该研究共纳入717例受试者（应答率71.7％），其中4.5％的受试者为确诊性哮喘，34.7％的受试者为可疑性哮喘，60.8％的受试者为无症状性哮喘。室内污染物暴露与哮喘呈正相关。那些居住在交通拥挤路段附近的（ORa =4.30 [95％可信区间1.45-12.71]，P <0.05），那些曾经暴露于火（ORa = 1.84 [95％可信区间 1.01-3.36]）和那些暴露于烟雾（ORa = 4.15 [95％可信区间1.42-12.12]）的受试者患哮喘的风险较高。房间早晨通风或禁止室内吸烟有助于预防哮喘。
   结论：这些结果表明，患哮喘或有呼吸道症状的风险不仅与室内污染有关，也与室外污染尤其是道路交通有关。
 

（杨冬 审校）
Rev Mal Respir. 2015 Jun 9. pii: S0761-8425(15)00232-6. doi: 10.1016/j.rmr.2014.11.073. [Epub ahead of print]

 

Asthma, indoor and outdoor air pollution: A pilot study in Lebanese school teenagers.
 

[Article in French]
Salameh P1, Karaki C2, Awada S3, Rachidi S3, Al Hajje A3, Bawab W3, Saleh N4, Waked M5.
 

Abstract
INTRODUCTION:Many studies have demonstrated that outdoor pollution might exacerbate respiratory symptoms and childhood asthma. Our objective was to evaluate the relationship between asthma and outdoor and indoor pollution.
METHODS:We undertook a survey in May-June 2012 about schoolchildren aged 12-19years in six Lebanese schools. This combined the International Study of Asthma and Allergies in Childhood (ISAAC) standardized questionnaire with other questions addressing outdoor and indoor exposure.
RESULTS:Among 717 subjects (response rate 71.7%), 4.5% had physician-diagnosed asthma, 34.7% had probable asthma and 60.8% were asymptomatic. Exposure to indoor contaminants was positively associated to asthma. The risk for asthma was higher in those residing near heavy road traffic (ORa=4.30 [95% CI 1.45-12.71], P<0.05), those previously exposed to fire (ORa=1.84 [95% CI 1.01-3.36]), and those exposed to smog (ORa=4.15 [95% CI 1.42-12.12]). Airing the house in the morning or in case of indoor smoking had a protective effect against asthma.
CONCLUSION:These results suggest that the risks of asthma or having respiratory symptoms are not only related to indoor pollution but also to outdoor pollution especially from road traffic.
 

Rev Mal Respir. 2015 Jun 9. pii: S0761-8425(15)00232-6. doi: 10.1016/j.rmr.2014.11.073. [Epub ahead of print]