哮喘联盟

   摘要
   这项一般性综述旨在调查主动和被动吸烟对儿童和成人哮喘发展的影响。孕期和产后被动吸烟促进儿童哮喘和喘息的发作。尤其孕期吸烟与儿童4岁之前的喘息发作相关联。相比之下，产后父母吸烟与儿童哮喘或喘息发作之间的关系的研究结果是不一致的。儿童时期被动吸烟促进成年时期哮喘的发生。在成人和青少年，主动吸烟似乎是促进哮喘发展的一个因素。在另一方面，无哮喘病史的非吸烟成年受试者被动吸烟有患哮喘的风险。人们对烟草烟雾作为哮喘病因的病理生理机制仍然知之甚少。戒烟是吸烟哮喘患者管理的重要组成部分，它有利于病情的控制。

 

（苏欣 审校）
Rev Mal Respir. 2015 Feb;32(2):110-137. doi: 10.1016/j.rmr.2014.07.014. Epub 2014 Oct 18.
 

Influence of tobacco smoking on the risk of developing asthma.
 

Underner M1, Perriot J2, Peiffer G3, Meurice JC4.

Author information
 

Abstract
The aim of this general review is to investigate the influence of active and passive smoking on the development of asthma in children and adults. Passive smoking during and after pregnancy facilitates the onset of childhood asthma and wheezing. In particular, smoking during pregnancy is associated with the occurrence of wheezing prior to the age of 4 years. In contrast, the results of studies on the relationship between parental smoking in the post-natal period and the onset of asthma or wheezing are discordant. Exposure to passive smoking during childhood facilitates the occurrence of asthma in adulthood. In adults and adolescents, active smoking appears to be a factor favoring the development of asthma. On the other hand, non-smoking adult subjects without history of asthma exposed to passive smoking have a risk of asthma. The pathophysiological mechanisms by which tobacco smoke is the cause of asthma are still poorly known. Smoking cessation is an essential component in the management of asthmatic subjects who smoke, facilitating the control of the disease.

Rev Mal Respir. 2015 Feb;32(2):110-137. doi: 10.1016/j.rmr.2014.07.014. Epub 2014 Oct 18.