哮喘联盟

   摘要
   背景：支气管扩张和哮喘在许多方面是不同的，但一些患者同时患有这两种疾病。目前评估支气管扩张对哮喘急性发作影响的研究很少。本研究的目的旨在调查支气管扩张对哮喘急性发作的影响。
   方法：共纳入了我院随访的2,270例哮喘患者，其中50例同时患有支气管扩张和哮喘。我们从2,220例哮喘但无支气管扩张的患者中选择50例年龄和性别匹配的患者作为对照组，基于每组总哮喘急性发作的年发生率，激素的年使用率，以及由于哮喘急性发作的急诊就诊和住院频率，评估哮喘急性发作和其严重程度。
   结果：50例患者（2.2%）同时患有支气管扩张和哮喘。同时患有支气管扩张和哮喘的患者哮喘急性发作的年发生率高于仅患有哮喘的患者（1.08±1.68 vs. 0.35±0.42，p=0.004）。同时患有支气管扩张和哮喘的患者由于哮喘急性发作的激素年使用率（0.9±1.54 vs. 0.26±0.36，p=0.006）和急诊就诊频率（0.46±0.84 vs. 0.02±0.13，p=0.001）也高于仅患有哮喘的患者。
   结论：支气管扩张与哮喘难以控制相关。
 

（杨冬 审校）
Tuberc Respir Dis (Seoul). 2014 Nov;77(5):209-14. doi: 10.4046/trd.2014.77.5.209. Epub 2014 Nov 28.

 

The effects of bronchiectasis on asthma exacerbation.
 

Kang HR1, Choi GS1, Park SJ1, Song YK1, Kim JM1, Ha J1, Lee YH1, Lee BH1, Kim SH1, Lee JH1.
 

ABSTRACT
BACKGROUND: Bronchiectasis and asthma are different in many respects, but some patients have both conditions. Studies assessing the effect of bronchiectasis on asthma exacerbation are rare. The aim of this study is to investigate the effect of bronchiectasis on asthma exacerbation.
METHODS: We enrolled 2,270 asthma patients who were followed up in our hospital. Fifty patients had bronchiectasis and asthma. We selected fifty age- and sex-matched controls from the 2,220 asthma patients without bronchiectasis, and assessed asthma exacerbation and its severity based on the annual incidence of total asthma exacerbation, annual prevalence of steroid use, and frequency of emergency room visits and hospitalizations due to asthma exacerbation in each group.
RESULTS: Fifty patients (2.2%) had bronchiectasis and asthma. The annual incidence of asthma exacerbation was higher in patients with asthma and bronchiectasis than in patients with asthma alone (1.08±1.68 vs. 0.35±0.42, p=0.004). The annual prevalence of steroid use (0.9±1.54 vs. 0.26±0.36, p=0.006) and the frequency of emergency room visits (0.46±0.84 vs. 0.02±0.13, p=0.001) due to asthma exacerbation were also higher in patients with asthma and bronchiectasis than in patients with asthma alone.
CONCLUSION: Bronchiectasis is associated with difficult asthma control.

Tuberc Respir Dis (Seoul). 2014 Nov;77(5):209-14. doi: 10.4046/trd.2014.77.5.209. Epub 2014 Nov 28.