哮喘联盟

   摘要
   背景：我们知道，对尼古丁的依赖作用（ND）对成功戒烟起着负面效应，而戒烟自我效能（SASE）则起着正面的影响，但是目前并没有确切的证据证实戒烟自我效能是如何在尼古丁依赖与成功戒烟之间发挥作用的。因此，本研究的目的是评估这种介导作用。
   方法：我们采用了病例对照的研究方法，共纳入了642例成功自主戒烟的病例和700例自主戒烟失败的病例作为对照。尼古丁依赖程度通过尼古丁依赖Fagerström测试量表（FTND）评估，戒烟自我效能则通过戒烟自我效能评估量表评估。我们将倾向评分作为回归分析模型的协变量以校正年龄、戒烟开始的时间、职业、教育程度以及婚姻状态等混杂因素的影响。采用Holm等推荐的KHB方法中的logistic回归模型将总效应分解为直接和间接（介导）效应。
   结果：将结果经上述提及的混杂因素进行校正后，戒烟自我效能在介导尼古丁依赖与成功戒烟之间的作用总得分为32.90%，而其它三项特定得分，即社会方面、情感方面以及成瘾性方面的介导作用得分分别为12.14%、35.64%和83.03%。
   结论：本研究的结果显示，戒烟自我效能在介导尼古丁依赖与成功自主戒烟之间发挥着部分效应。通过鼓励吸烟者提高戒烟自我效能可增加戒烟的成功率。
 

（刘国梁 审校）
Eur J Public Health. 2014 Nov 12. pii: cku183. [Epub ahead of print]


 

Mediation of smoking abstinence self-efficacy on the association of nicotine dependence with smoking cessation.
 

Li S1, Fang L2, Zhou Y1, Pan L1, Yang X1, Li H1, Wang Q1, Jiang F1, Zhang N1, Han M1, Jia C3.
 

ABSTRACT
BACKGROUND: The nicotine dependence (ND) has negative and smoking abstinence self-efficacy (SASE) has positive effects on successful smoking cessation, but scant data is now available for what is the mediating role of SASE on the relationship between ND and successful smoking cessation. The aim of this study was to assess the abovementioned mediation.
METHODS: A case-control study was conducted with 642 successful spontaneous quitters as the cases, and 700 failed spontaneous quitters as the controls. ND and SASE were evaluated by Fagerström Test for Nicotine Dependence (FTND) scale and SASE scale, respectively. Propensity score as covariate in the regression model was used to adjust for potential confounders of age, age of smoking initiation, occupation, educational level and marital status. Total effect was decomposed into direct and indirect (mediating) effect using logistic regression based on the KHB method proposed by Holm et al.
RESULTS: After adjusting for the aforementioned potential confounders, the mediating effects among the total effect of ND on successful spontaneous smoking cessation were 32.90%, 12.14%, 35.64% and 83.03% for the total score of SASE and its three context-specific situation scores, i.e. positive/social situation, negative/affective situation and habit/addictive situation, respectively.
CONCLUSIONS: This study indicates that SASE has a partial mediating effect on the association of ND with successful spontaneous smoking cessation. To boost the smokers' SASE could increase the probability of successful smoking cessation.
 

Eur J Public Health. 2014 Nov 12. pii: cku183. [Epub ahead of print]