哮喘联盟

   摘要
   目的：虽然吸烟对哮喘患者有副作用，但是哮喘患者群体中吸烟者所占的比例仍高于正常人群体。焦虑敏感症（害怕唤起相关的感觉）与吸烟和哮喘均相关，但是至今没有研究表明这三者之间的相互作用。所以，本研究的目的是评估焦虑敏感症是否是哮喘的发生与吸烟状态两者之间的媒介。
   方法：本研究是对来自包括非吸烟者、吸烟者、有哮喘和无哮喘患者的三个数据库资料的二次分析（总例数为433；56.3%为女性；平均年龄为34.01岁，SD = 13.9）。所有受试者均提供其哮喘诊断结果及吸烟状况相关信息，并进行自我报告测量。
   结果：与预料的结果一致，将结果对性别、种族及年龄等变量进行校正后，哮喘诊断通过焦虑敏感症对吸烟状态有着显著的间接效应（95% CI = .07 to .48）。
   结论：本研究的结果表明，哮喘诊断与吸烟状态之间的联系可能部分是由焦虑敏感症介导的。因此，我们提议将治疗焦虑敏感症作为吸烟合并哮喘患者重要的干预治疗目标。
 

（苏楠 审校）
J Asthma. 2014 Nov 6:1-29. [Epub ahead of print]

 

Anxiety Sensitivity as a Mediator of the Association between Asthma and Smoking.
 

Avallone KM1, McLeish AC.
 

ABSTRACT
OBJECTIVE: Despite its negative effects, smoking is more common among individuals with asthma compared to those without. Anxiety sensitivity (fear of arousal-related sensations) is associated with both smoking and asthma; however, no research, to date, has examined the interplay between these three factors. Thus, the purpose of the current study was to evaluate the mediating role of anxiety sensitivity in the association between asthma diagnosis and smoking status.
METHODS: The current study was a secondary analysis of data from three existing datasets of non-smokers and smokers with and without asthma (n = 433; 56.3% female, Mage = 34.01 years, SD = 13.9). Participants provided information on their asthma diagnosis status and smoking status and completed self-report measures.
RESULTS: As hypothesized, after controlling for gender, race, and age, there was a significant indirect effect of asthma diagnosis on smoking status through anxiety sensitivity (95% CI = .07 to .48).
CONCLUSIONS: These results indicate that the association between asthma diagnosis and smoking status appears to be driven, in part, by anxiety sensitivity and suggest that anxiety sensitivity may serve as an important target for prevention and intervention efforts for smokers with asthma.

J Asthma. 2014 Nov 6:1-29. [Epub ahead of print]