哮喘联盟

   摘要
   研究目的：儿童哮喘控制包括两部分内容：疾病危害及疾病风险，本研究旨在阐述这两部分与家长生活质量的相关性。
   研究方法：本横断面研究招募对象为西班牙多家初级护理中心4-14岁患有活动性哮喘的儿童。根据第三届国家哮喘专家小组报告内容进行哮喘控制评估，将“疾病危害”分为三个等级（哮喘控制良好，哮喘部分控制，哮喘控制不佳），“疾病风险”分为高和低两种。家长生活质量采用特定的儿童支气管哮喘家庭影响调查问卷（IFABI-R）进行评估。哮喘控制与家长生活质量的相关性通过多元回归模型分析，该分析模型经校正适用于其他社会与家庭变量。
   研究结果：研究分析了408名儿童患者数据。与哮喘控制良好组相比，部分控制组家长的生活质量受到影响，表现为IFABI-R分值在所有层面均上升：功能17.2%（p＜0.001），情感10.4%（p=0.021）以及社会职业6.8%（p=0.056）。而哮喘控制不佳组上升程度更大：功能24.3%（p=0.001），情感18.9%（p=0.008）以及社会职业11.5%（p=0.036）。“疾病风险”与家长生活质量独立相关。而在评估哮喘控制的所有元素中，只有复发性哮喘危机与家长生活质量独立相关。
   结论：在哮喘控制中，无论“疾病危害”还是“疾病风险”均与家长生活质量逐步相关。相比采用单独元素评估哮喘控制，哮喘控制的全面评估更为重要。
 

（刘国梁 审校）
J Asthma. 2014 Aug 11:1-7. [Epub ahead of print]

 

Association between quality of life in parents and components of asthma control in children.
 

Cano-Garcinuño A1, Bercedo-Sanz A, Mora-Gandarillas I, Callén-Blecua MT, Castillo-Laita JA, Forns-Serrallonga D, Casares-Alonso I, Alonso-Bernardo LM, García-Merino A, Moneo-Hernández I, Cortés-Rico O, Tauler-Toro E, Carvajal-Urueña IL, Morell-Bernabé JJ, Martín-Ibáñez I, Rodríguez-Fernández-Oliva CR, Asensi-Monzó MT, Fernández-Carazo C, Murcia-García J, Durán-Iglesias C, Montón-Álvarez JL, Domínguez-Aurrecoechea B, Praena-Crespo M.
 

ABSTRACT
OBJECTIVE: Describe the association between parents' quality of life and the two components of asthma control in children: impairment and risk.
METHODS: Cross-sectional study with children between 4 and 14 years of age with active asthma recruited at primary care centers in Spain. Asthma control was assessed according to the Third National Asthma Expert Panel Report, classifying "impairment" in three levels (well-controlled asthma, partially controlled, and poorly controlled), and "risk" as high or low. The parents' quality of life was evaluated using the specific Family Impact of Childhood Bronchial Asthma Questionnaire instrument (IFABI-R). The association between asthma control and the parents' quality of life was analyzed using multivariate regression models adjusted for other social and family variables.
RESULTS: Data from 408 children were analyzed. The parents' quality of life was affected in the partially controlled asthma group when compared with well-controlled asthma, as showed by an increase in IFABI-R scores in all dimensions: functional 17.2% (p < 0.001), emotional 10.4% (p = 0.021), and socio-occupational 6.8% (p = 0.056). The differences were higher in poorly controlled asthma compared with well-controlled asthma: functional 24.3% (p = 0.001), emotional 18.9% (p = 0.008), and socio-occupational 11.5% (p = 0.036). The "risk" component was independently associated with the parents' quality of life. Of all the elements used to assess the control, the only one independently associated with the parents' quality of life was recurrent asthma crisis.
CONCLUSIONS: In asthma control, both "impairment" and "risk" in children are gradually associated with the parents' quality of life. The global assessment of the control surpasses the importance of each individual element used in this assessment.
 

J Asthma. 2014 Aug 11:1-7. [Epub ahead of print]