哮喘联盟

   摘要
   目的：抗阻力负荷检测实现了对精神躯体结果个体差异的分析。本研究的目的旨在评估抗阻力负荷检测在持续性哮喘儿童中的可靠性和预测性，这些儿童均完成了多期测试。
   方法：北卡大学夏洛特分校和俄亥俄大学机构审查委员会批准本研究协议。在75例年龄为8～15岁哮喘儿童中进行吸气电阻负荷的检测。每一例儿童参加约每两周一次的四个实验期。采用多因素分析描述工作绩效的预测因素。
   结果：评估每例儿童进行抗阻力负荷检测的安全性，并在以下2组儿童中分析负荷检测结果的预测因素：一组为可靠地完成了所有4期检测的儿童(n=31)，另一组为可靠地完成了≤3期检测的儿童(n=44)。在负荷检测结果中预测了38.7%（多重 R = 0.62, p = .004）差异的变量中，其中3个因素（发育、症状和依从性）占到了63%的差异，且这些因素在80.6%的儿童中正确分类了可靠或较少可靠执行(x(12) = 28.88, p = .004)。
   结论：认知和生理发育、症状评估以及依从性相关的行为：(1)在变量中他们的相互关系占了很大的比例，影响哮喘儿童气流阻塞的感知;(2)区分或多或少可靠的完成阻力负荷检测任务的儿童。
 

（林江涛 审校）
J Asthma.2014 Aug 21:1-36. [Epub ahead of print]

 

Reliability and Predictors of Resistive Load Detection in Children with Persistent Asthma: A Multivariate Approach.
 

Harver A1, Dyer A, Ersek J, Kotses H, Humprhies TC.
 

Abstract
OBJECTIVE: Resistive load detection tasks enable analysis of individual differences in psychophysical outcomes. The purpose of this study was to determine both the reliability and predictors of resistive load detection in children with persistent asthma who completed multiple testing sessions.
METHODS: Both UNC Charlotte and Ohio University institutional review boards approved the research protocol. The detection of inspiratory resistive loads was evaluated in 75 children with asthma between 8 and 15 years of age. Each child participated in four experimental sessions that occurred approximately once every two weeks. Multivariate analyses were used to delineate predictors of task performance.
RESULTS: Reliability of resistive load detection was determined for each child, and predictors of load detection outcomes were investigated in two groups of children: those who performed reliably in all four sessions (n = 31) and those who performed reliably in three or fewer sessions (n = 44). Three factors (development, symptoms, and compliance) accounted for 66.3% of the variance among variables that predicted 38.7% of the variance in load detection outcomes (Multiple R = 0.62, p = .004) and correctly classified performance as reliable or less reliable in 80.6% of the children (x(12) = 28.88, p = .004).
CONCLUSIONS: Cognitive and physical development, appraisal of symptom experiences, and adherence-related behaviors 1) account for a significant proportion of the interrelationships among variables that affect perception of airflow obstruction in children with asthma and 2) differentiate between children who perform more or less reliably in a resistive load detection task.
 

J Asthma.2014 Aug 21:1-36. [Epub ahead of print]