哮喘联盟

   摘要
   目的：尽管哮喘与心理疾病发生相关，但该相关性可能被哮喘控制不佳所干扰。本研究旨在比较哮喘控制良好儿童与健康儿童的焦虑、抑郁以及自尊水平低下的发生情况。
   机构：一家综合医院的哮喘专科门诊。
   患者：70例大多哮喘得到良好控制的患者和70例匹配的健康对照者。
   干预：给予哮喘患者全面的哮喘教育，管理以及随访。
   主要结果评估：采用荷兰儿童抑郁量表(CDI)、修订儿童恐惧调查表(RFSC)、儿童(SPC-C)和青少年(SPC-A)自我感知量表以及儿童状态-特质焦虑量表(STAIC)进行评估。通过哮喘控制调查表评估哮喘控制情况。
   结果：哮喘组和对照组间的总分无显著性差异[95% CI ：CDI( -0.2 — 2.9)，RFSC(-5.9 — 11.2) , SPC-C (-19.9 —6.3), SPC-A (-24.1 — 5.0) , STAIC (-2.7 —0.01)]。哮喘组和对照组间在超过截点水平的临床相关焦虑(13.3 vs 13.0%, p=0.605)、抑郁(12.9 vs 5.7%, p=0.243)或自尊水平低下(21.4 vs 12.9%, p=0.175)评分也无显著性差异。哮喘控制不佳与CDI(p=0.012)和特质焦虑症状(p<0.001)显著相关。
   结论：加入全面哮喘管理计划的哮喘控制良好的儿童并未增加焦虑、抑郁以及自尊水平低下的风险。哮喘合并心理疾病的早期报告可能与哮喘控制不佳相关。
 

（林江涛 审校）
Arch Dis Child. 2014 May 8. doi: 10.1136/archdischild-2013-305396. [Epub ahead of print]

 

Anxiety, depression and self-esteem in children with well-controlled asthma: case-control study.
 

Letitre SL1, de Groot EP, Draaisma E, Brand PL.
 

ABSTRACT
OBJECTIVE: Although asthma has been linked to psychological morbidity, this relationship may be confounded by poor asthma control. We aimed to compare the prevalence of anxiety, depression and low level of self-esteem in children with well-controlled asthma with that of healthy peers.
SETTING: Dedicated asthma clinic in a general hospital.
PATIENTS: 70 patients with mostly well-controlled asthma and 70 matched healthy controls.
INTERVENTIONS: Comprehensive asthma education, management and follow-up for asthma patients.
MAIN OUTCOME MEASURES: Validated Dutch versions of the Childhood Depression inventory (CDI), Revised Fear Survey for Children (RFSC), Self Perception Profile for Children (SPC-C) and Adolescents (SPC-A) and State-Trait Anxiety Inventory for Children (STAIC). Asthma control assessed by asthma control questionnaire.
RESULTS: No significant differences were found in total scores between asthmatics and controls (95% CI for difference -0.2 to 2.9 for CDI, -5.9 to 11.2 for RFSC, -19.9 to 6.3 for SPC-C, -24.1 to 5.0 for SPC-A and -2.7 to 0.01 for STAIC). There were also no significant differences between asthmatics and controls in the prevalence of scores exceeding cut-off levels for clinically relevant anxiety (13.3 vs 13.0%, p=0.605), depression (12.9 vs 5.7%, p=0.243) or low self-esteem (21.4 vs 12.9%, p=0.175). A significant correlation was found between poorer asthma control and CDI (p=0.012) and anxiety trait symptoms (p<0.001).
CONCLUSIONS: Children with well-controlled asthma enrolled in a comprehensive asthma management programme do not have an increased risk of anxiety, depression and poor self-esteem. Earlier reports of psychological comorbidity in asthma may have been related to inadequately controlled asthma.
 

Arch Dis Child. 2014 May 8. doi: 10.1136/archdischild-2013-305396. [Epub ahead of print]