哮喘联盟

   摘要
   背景：哮喘严重程度是评估哮喘护理和处理的一项关键指标。严重程度可能会随时间而变化。定期评估哮喘严重程度对监测哮喘患者的健康和幸福状况非常重要。
   目的：评估基于人群的哮喘严重程度，并鉴定儿童和成人哮喘患者的相关危险因素。
   方法：我们采用2006年～2010年的BRFSS儿童和成人哮喘患者的回访研究数据。哮喘严重程度分为间歇性或持续性。我们采用多元逻辑回归鉴定哮喘相关危险因素。
   结果：总体来说，68%的哮喘患者为持续性哮喘，且在0～4岁儿童更普遍（71.8%，患病率比PR=1.3）。目前成人哮喘患者中，持续性哮喘更多见于以下情况：45岁及以上的患者（年龄45～54: 69.4%; PR=1.1；年龄55～64: 72.6%; PR=1.2；年龄65岁以上: 77.8%; PR=1.3）；家庭年收入低于$15,000(74.1%; PR=1.1);初次诊断年龄在55岁及以上（初次诊断年龄55～64: 80.4%; PR=1.1, 65岁以上: 81.5%; PR=1.1）。暴露于二手烟环境（SHS）的吸烟者持续性哮喘的患病率也较高(74.7%; PR=1.1)；慢性阻塞性肺疾病（COPD）患者持续性哮喘的患病率也较高(77.1%; PR=1.2)。
   结论：接近2/3的儿童和成人哮喘患者为持续性哮喘。鉴定哮喘相关风险因素有助于改进靶向性干预和策略，以降低增加哮喘严重性的可变预测因素（低收入、吸烟和SHS）。这些策略有助于提高哮喘护理水平和生活质量。
 

（刘国梁 审校）
J Asthma. 2014 Feb 10. [Epub ahead of print]

 

Assessing asthma severity among children and adults with current asthma.
 

Zahran HS, Bailey C, Qin X, Moorman JE.
 

ABSTRACT
ABSTRACT BACKGROUND：Asthma severity is a key indicator to assess asthma care and management. Severity status may vary over time. Assessing asthma severity periodically is important for monitoring the health and well-being of people with asthma.
OBJECTIVE：To assess population-based asthma severity and to identify related-risk factors among children and adults with asthma.
METHODS：We used the 2006 to 2010 BRFSS child and adult Asthma Call-back Survey. Asthma severity was classified as intermittent or persistent. We performed multivariate logistic regression to identify related-risk factors.
RESULTS：Overall, 63.8% of persons with asthma had persistent asthma. Persistent asthma was more prevalent among children aged 0-4 years (71.8%; prevalence rate ratio [PR]=1.3). Among adults with current asthma, persistent asthma was more prevalent among those who were 45 years or older (aged 45-54: 69.4%; PR=1.1, aged 55-64: 72.6%; PR=1.2, and aged 65+: 77.8%; PR=1.3); annual household incomes of <$15,000 (74.1%; PR=1.1); and first diagnosed at age 55 years or older (first diagnosed at age 55-64: 80.4%; PR=1.1, at age 65+: 81.5%; PR=1.1). The prevalence of persistent asthma was also higher among current smokers who were also exposed to secondhand smoke (SHS) (74.7%; PR=1.1); and among those with Chronic Obstructive Pulmonary Disease (COPD) (77.1%; PR=1.2).
CONCLUSIONS：Nearly two-thirds of children and adults with asthma had persistent asthma. Identifying related-risk factors could help improve targeted interventions or strategies to reduce modifiable predictors (low income, smoking, and SHS) of increased asthma severity. Such strategies could improve asthma care and quality of life.
 

J Asthma. 2014 Feb 10. [Epub ahead of print]