哮喘联盟

   摘要
   简介：虽然哮喘患儿的入院治疗在高收入国家仍是一个重大问题，但在低-中等收入国家（LMIC）这一问题更加严重。然而，以往旨在确定儿童哮喘入院治疗预测因子的研究主要在高收入国家进行，而且这一结果可能并不适用于LMIC。
   方法：在一项前瞻性队列研究中，我们旨在确定哮喘儿童住院治疗的预测因子，包括父母对哮喘措施的了解程度和母亲的抑郁程度。研究人群是住在哥伦比亚波哥大，因急性哮喘发作住院超过6个月的1～18岁的儿童。
   结果：总计纳入101例患者，其中37例（36.6%）在随访期间因哮喘至少住院治疗1次。校正患者年龄后，在前12个月养狗的人、前6个月哮喘严重度、母亲过敏性鼻炎、母亲受教育程度、父母对哮喘措施了解程度以及母亲抑郁程度等因素中，我们发现，母亲吸烟（IRR, 3.12；95%可信区间 [95% CI]，1.12-8.68；P = 0.029）是随访期间因哮喘急性发作入院治疗的唯一独立预测因子。
   结论：因急性发作而住院的哮喘拉丁美洲患者中，大约三分之一的患者随访期间至少1次因哮喘而住院，且母亲吸烟是这些住院患者的唯一独立预测因子。
 

（苏楠 审校）
Pediatr Pulmonol. 2013 Dec 27. doi: 10.1002/ppul.22936. [Epub ahead of print]

 

Predictors of hospitalization for asthma in children: Results of a 1-year prospective study.
 

Rodríguez-Martínez CE, Sossa-Briceño MP, Castro-Rodriguez JA.
 

Abstract
INTRODUCTION: Although hospital admissions for pediatric asthma constitute a significant problem in high-income countries, they are an even greater health problem in low- and middle-income countries (LMIC). However, previous studies that aimed to identify predictors of hospital admission for asthma in children have mainly been conducted in high-income countries, and these findings might not be applicable to LMIC.
METHODS: In a prospective cohort study, we aimed to identify predictors of hospital admission for asthma, including measures of parental knowledge about asthma and maternal depression level, in a population of children aged 1-18 years living in urban Bogota, Colombia hospitalized for acute asthma symptoms, over a 6-month period.
RESULTS: Out of the total of 101 included patients, 37 (36.6%) had at least one hospital admission for asthma during the year following admission. After controlling for the age of the patients, dog ownership in the previous 12 months, asthma severity variables in the previous 6 months, maternal allergic rhinitis, level of maternal education, and measures of parental knowledge about asthma and maternal depression level, we found that maternal smoking (IRR, 3.12; 95% confidence interval [95% CI], 1.12-8.68; P = 0.029) was the only independent predictor of hospital admissions due to asthma exacerbations in the year following admission to the study.
CONCLUSIONS: In a population of asthmatic Latino children admitted to hospital for an asthma exacerbation, approximately one-third of the patients had at least one hospital admission for asthma during the year following admission, and maternal smoking was the only independent predictor of these hospitalizations.
 

Pediatr Pulmonol. 2013 Dec 27. doi: 10.1002/ppul.22936. [Epub ahead of print]