哮喘联盟

   摘要
   目的：旨在确定 a）哮喘患者补充和替代性药物(CAM)的使用率，b）伴发的慢性疾病和哮喘严重程度是否与CAM使用有关。
   方法：这项横断面的研究数据来自参加过2009年行为危险因素监控系统(BRFSS)和2009年哮喘电话随访调查(ACBS)的15276例成年人。采用二元逻辑回归分析确定伴发慢性疾病和哮喘严重程度是否与CAM使用有关（是/否）。模型的协变量是年龄、性别、收入和教育程度。
   结果：26%的调查者报告至少使用过CAM中的一种。报告最多的一种CAM是呼吸锻炼(19.8%)。结果显示伴发的心血管疾病、糖尿病和中风都与CAM使用无关，但个别哮喘症状严重使用CAM的可能性更大（比值比OR = 1.05,，95%可信区间CI为1.04, 1.05）。
   结论：哮喘患者最常用的CAM治疗方法（呼吸技巧，维生素）不会构成安全风险。伴发的慢性病不会促使哮喘患者寻求非常规的治疗方法。未处理/处理不当的疾病或药物的副作用可能是导致CAM使用增加哮喘严重程度的因素。

（刘国梁 审校）
J Asthma. 2013 Dec 5. [Epub ahead of print]

Complementary and Alternative Medicine Use and Asthma: Relation to Asthma Severity and Comorbid Chronic Disease.

Morgan W, Center H, Arms-Chavez C, Lobello SG.

ABSTRACT
OBJECTIVE: To determine a) the prevalence of complementary and alternative medicine (CAM) use among people with asthma, and b) if comorbid chronic disease and asthma severity are associated with CAM use.
METHOD: This cross-sectional study utilized data from n=15,276 adults who participated in the 2009 Behavioral Risk Factor Surveillance System (BRFSS) and the 2009 Asthma Callback Survey (ACBS). Binary Logistic regression was used to determine if comorbid disease and asthma severity were associated with CAM use (yes/no). Model covariates were age, sex, income, and education.
RESULTS: About 26% of respondents report using at least one form of CAM. The most frequently reported form of CAM use reported is breathing exercises (19.8%). The results indicate that neither comorbid cardiovascular disease, diabetes, nor stroke are related to CAM use, but individuals with more severe asthma symptoms were more likely to use CAM (OR = 1.05, 95% CI 1.04, 1.05).
CONCLUSIONS: CAM remedies most often reported by people with asthma (breathing techniques, vitamins) are unlikely to pose safety risks. Comorbid chronic disease does not motivate people with asthma to seek unconventional remedies. The increase in CAM use with asthma severity prompts questions about factors that might drive this behavior, such as untreated/inadequately treated disease, or medication side effects.

J Asthma. 2013 Dec 5. [Epub ahead of print]