哮喘联盟

   摘要
   简介：支气管哮喘是常见的慢性病，各年龄段人群均可发病。哮喘控制不良可能导致患者经常到急诊科（ED）寻求紧急的控制措施。
   目的：该研究旨在确定与哮喘控制不良相关的因素。
   方法：共纳入450例到急诊科就诊的受试者。除评估哮喘的严重程度等级外，我们还采用哮喘控制测试（ACT）评分对过去几个月来在ED寻求哮喘控制的每位患者进行了评估。采用独立t检验和方差分析评估人口统计学特征和临床特征在哮喘控制评分的差异中是否有统计学意义。哮喘控制评分对人口统计学特征和临床特征的依赖性采用逐步回归模型进行分析。
   结果：不同急诊科就诊频率和哮喘严重程度者的哮喘控制评分存在差异（P=0.001）。结果发现，受试者年龄，ED就诊次数，重度持续性、中度持续性、轻度持续性，接受哮喘药物治疗的教育程度及哮喘疾病的教育程度均明显影响哮喘控制评分。例如，当受试者患有重度持续性哮喘时哮喘控制评分预计下降10.688。同样，当受试者患有中度持续性哮喘时哮喘控制评分预计下降5.647。
   结论：该研究发现多个可能解释哮喘控制不良的相关因素。

（苏楠 审校）
Clin Respir J. 2013 Dec 6. doi: 10.1111/crj.12090. [Epub ahead of print]

Factors Associated With Poor Asthma Control Among Asthmatic Patient Visiting Emergency Department.

Ahmed AE, Al-Jahdali H, Al-Harbi A, Khan M, Ali Y, Shimemeri AA, Al-Muhssen S, Halwani R.

Abstract
INTRODUCTION: Bronchial asthma is a common chronic disease that affects people of all ages. Insufficient asthma control may cause frequent Emergency Department (ED) visit by patients who seek crisis management of their asthma.
OBJECTIVES: This study aims to identify the factors associated with poor asthma control.
METHODS: We enrolled 450 participants who visited (ED) for asthma management.. Besides assessing the asthma severity classification, we assess each participant for asthma control over the months preceding ED visit using Asthma Control Test (ACT) score. We employed an independent t-test and ANOVA to assess if the differences in asthma control scores by demographic and clinical characteristics are statistically significant. The dependence of asthma control scores on demographic and clinical characteristics had been investigated with stepwise regression model.
RESULTS: There are differences in asthma control scores by the number of ED visits and severity of asthma classification (p-values=0.001). It was found that participant age, multiple ED visits, severe persistent, moderate persistent, mild persistent, received education about asthma medication, and received education about asthma disease were greatly affected asthma control scores. For instance, the asthma control is predicted to decrease by 10.688 when participant had severe persistent asthma. Similarly, the asthma control is predicted to decrease by 5.647 when the participant had moderate persistent asthma.
CONCLUSIONS: This study identified many factors that may explain insufficient asthma control.

Clin Respir J. 2013 Dec 6. doi: 10.1111/crj.12090. [Epub ahead of print]