哮喘联盟

   摘要：
   在哮喘以及慢性阻塞性肺疾病中压力定量吸入器和干粉吸入器是使用最广泛的吸入疗法装置；每一种装置都有一定的优点和缺点影响着他们的使用。由于这些装置的推动促进了呼吸致动或呼吸激活定量雾化吸入器的发展。本综述介绍了呼吸致动吸入器的历史，研发和技术现状，可用性、吸入方法以及病人意愿的研究，肺部沉积和对肺功能影响。本文论述了呼吸致动吸入器在哮喘和慢性阻塞性肺疾病中、以及在儿童和老年人群中的使用情况；并采用简单经济评估方法，通过了解与该装置相关的长期成本效益，以正确评价呼吸驱动吸入器的临床疗效和使用容易程度。
 

（林江涛 审校）
Expert Rev Respir Med. 2013 Dec 10. [Epub ahead of print]

Use of breath-actuated inhalers in patients with asthma and COPD - an advance in inhalational therapy:. a systematic review
 

Salvi S, Gogtay J, Aggarwal B.
 

ABSTRACT
The pressurized metered dose inhalers and dry powder inhalers are the most widely used devices for inhalation therapy in asthma and chronic obstructive pulmonary disease; each of these devices have certain advantages and disadvantages that impact their use. Motivation from the virtues of these devices led to the development of breath-actuated or breath-activated metered dose inhalers. A history of the breath-actuated inhalers, the development and technical aspects, studies about the usability, inhalation technique and patient preference, lung deposition and impact on lung function are presented in this review article. This review presents the use of breath-actuated inhalers in asthma and chronic obstructive pulmonary disease and in children and elderly; and a brief economic evaluation aims to put the clinical efficacy and ease-of-use of the breath-actuated inhaler into perspective by understanding the long-term cost benefits associated with this device.
 

Expert Rev Respir Med. 2013 Dec 10. [Epub ahead of print]