哮喘联盟

   摘要
   我们对居住在土耳其埃斯基谢希尔市空气污染水平不同地区（郊区、市区和城市交通区域）的三组学生儿童进行环境空气对健康影响的研究。本研究纳入了来自16所公立小学的1880名学生，年龄9～13岁。该两季节研究从2008年一月到2009年三月进行实施。根据2008国际哮喘和过敏症儿童问卷研究判断哮喘、鼻炎、湿疹症状。夏季和冬季分别对每个儿童进行肺功能检测，并同时以被动采样法测定环境大气中臭氧（O3）、二氧化氮（NO2）和二氧化硫（SO2）。采用多因素logistic回归分析评估空气污染对学校儿童肺功能损害和症状的影响。与城市交通区域相比，更多郊区和市区女孩存在肺功能损害（仅限于夏季评估），郊区与城市交通区域相比的比值比（OR）=1.49,[95%可信区间（CI）1.04-2.14]，市区与城市交通区域相比的OR=1.69,；95%（CI 1.06-2.71）。仅在夏季评估的女孩中发现空气臭氧浓度与肺功能损害（增长10ugm（-3））明显相关[OR=1.11 (95 % CI 1.03-1.19)]。在男孩和冬季评估中没有发现相关性。任何检测的空气污染物和近期晓鸣音、近期鼻炎和近期发痒性皮疹之间并无关联。本研究结果显示臭氧含量增加可能导致学龄儿童亚急性肺功能损害。
 

（刘国梁 审校）
Environ Sci Pollut Res Int. 2013 Sep;20(9):6455-67. doi: 10.1007/s11356-013-1674-1. Epub 2013 Apr 17.


 

Effects of air pollution on lung function and symptoms of asthma, rhinitis and eczema in primary school children.
 

Altuğ H, Gaga EO, Döğeroğlu T, Ozden O, Ornektekin S, Brunekreef B, Meliefste K, Hoek G, Van Doorn W.
 

Abstract
Health effects of ambient air pollution were studied in three groups of schoolchildren living in areas (suburban, urban and urban-traffic) with different air pollution levels in Eskişehir, Turkey. This study involved 1,880 students aged between 9 and 13 years from 16 public primary schools. This two-season study was conducted from January 2008 through March 2009. Symptoms of asthma, rhinitis and eczema were determined by the International Study of Asthma and Allergies in Childhood questionnaire in 2008. Two lung function tests were performed by each child for summer and winter seasons with simultaneous ambient air measurements of ozone (O3), nitrogen dioxide (NO2) and sulfur dioxide (SO2) by passive sampling. Effects of air pollution on impaired lung function and symptoms in schoolchildren were estimated by multivariate logistic regression analyses. Girls with impaired lung function (only for the summer season evaluation) were more observed in suburban and urban areas when compared to urban-traffic area ([odds ratio (OR) = 1.49; 95 % confidence interval (CI) 1.04-2.14] and [OR = 1.69 (95 % CI 1.06-2.71)] for suburban vs. urban-traffic and urban vs. urban-traffic, respectively). Significant association between ambient ozone concentrations and impaired lung function (for an increase of 10 μg m(-3)) was found only for girls for the summer season evaluation [OR = 1.11 (95 % CI 1.03-1.19)]. No association was found for boys and for the winter season evaluation. No association was found between any of the measured air pollutants and symptoms of current wheeze, current rhinoconjunctivitis and current itchy rash. The results of this study showed that increasing ozone concentrations may cause a sub-acute impairment in lung function of school aged children.
 

Environ Sci Pollut Res Int. 2013 Sep;20(9):6455-67. doi: 10.1007/s11356-013-1674-1. Epub 2013 Apr 17.