哮喘联盟

   摘要
   背景：吸烟是慢性阻塞性肺疾病的一个重要的危险因素。但是在中国对于COPD吸烟者群体确只有很少的戒烟措施。本研究的目的旨在评价在中国戒烟行为干预的预防作用和COPD吸烟者潜在的影响因素。
   方法：一项随机对照戒烟试验，共纳入3562例当前吸烟的COPD患者，随机分为干预组(给予行为干预)和对照组(给予常规治疗)，为期2年。主要疗效终点为从第24个月开始到第30个月结束时的彻底持续戒烟率。受试者随访到第48个月。
   结果：从第24个月到第30个月接受行为干预的受试者的持续戒烟率显著高于接受常规治疗的对照组(46.4% vs 3.4%, p < 0.001)。第24个月到第36个月(45.8% vs 4.0%)和第24个月到第48个月(44.3% vs 5.1%)干预组的戒烟率显著高于对照组。家庭成员或家庭医师/护士吸烟被认定为是影响戒烟的首要因素。
   结论：行为干预可使COPD患者戒烟率加倍，且该方法在全科医生中的依从性良好。家庭成员和家庭医师吸烟是影响戒烟的主要危险因素。
 

（林江涛 审校）
BMC Fam Pract. 2013 Jun 27;14:91. doi: 10.1186/1471-2296-14-91.

 

Supporting smoking cessation in chronic obstructive pulmonary disease with behavioral intervention: a randomized controlled trial.
 

Lou P, Zhu Y, Chen P, Zhang P, Yu J, Zhang N, Chen N, Zhang L, Wu H, Zhao J.
 

Abstract
BACKGROUND:Cigarette smoking is the major risk factor for chronic obstructive pulmonary disease (COPD). But a fewer smoking cessation measures were conducted in communities for smokers with COPD in China. The aim of our study was to assess the preventive effects of behavioral interventions for smoking cessation and potential impact factors in smokers with COPD in China.
METHODS: In a randomised controlled smoking cessation trial 3562 patients with COPD who were current smoker were allocated to intervention group received behavioral intervention and control group received the usual care for two years. The primary efficacy endpoint was the complete and continuous abstinence from smoking from the beginning of month 24 to the end of month 30. Participants were followed up at month 48.
RESULTS: Continuous smoking abstinence rates from month 24 to 30 were significantly higher in participants receiving behavioral intervention than in those receiving usual care (46.4% vs 3.4%, p < 0.001). Continuous abstinence rates from months 24 to 36 (45.8% vs 4.0%) and months 24 to 48 (44.3% vs 5.1%) were also higher in participants receiving behavioral intervention than in those control group. Family members or family physicians/nurses smoking were first identified to influence smoking cessation.
CONCLUSIONS: Behavioral intervention doubled the smoking cessation rate in patients with COPD and was complied well by the general practitioners. The family members and family physicians/nurses smoking were the main risk factors for smoking cessation.
 

BMC Fam Pract. 2013 Jun 27;14:91. doi: 10.1186/1471-2296-14-91.