被动吸烟增加患糖尿病危险
2009/02/02
2008年“Diabetes Care”杂志中一篇日本的研究文献报道，在工作场所被动吸烟与糖尿病发生危险的增加有相关性。
在“促进职业健康人口策略及疾病高危因素研究”中，研究者调查了一组参与者的数据并进行分析，评估纳入者在工作场所被动吸烟的状态，探讨被动吸烟对糖尿病发生率的影响。
结果显示，在6498位研究对象中，共有229位在平均随访3.4年中患上糖尿病。与工作场所无吸烟暴露的个体相比，被动吸烟者患糖尿病的多元校正危险比为1.81（P=0.028）。
因此，在工作场所被动吸烟会增加糖尿病的发病危险。
（心泉）
附摘要:
Diabetes Care. 2008 Apr;31(4):732-734. Epub 2008 Jan 30
Diabetes Care. 2008 Apr;31(4):732-734. Epub 2008 Jan 30
A prospective study of passive smoking and risk of diabetes in a cohort of workers: the High-Risk and Population Strategy for Occupational Health Promotion (HIPOP-OHP) study.
Hayashino Y, Fukuhara S, Okamura T, Yamato H, Tanaka H, Tanaka T, Kadowaki T, Ueshima H; HIPOP-OHP Research Group.
Department of Epidemiology and Healthcare Research, Kyoto University Graduate School of Medicine, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan. hayasino-y@umin.net
OBJECTIVE: We investigated the impact of active smoking and exposure to passive smoke on the risk of developing diabetes.
RESEARCH DESIGN AND METHODS: Data were analyzed from a cohort of participants in the High-Risk and Population Strategy for Occupational Health Promotion Study (HIPOP-OHP) conducted in Japan from 1999 to 2004. Active and passive smoking status in the workplace was evaluated at baseline.
RESULTS: Of 6,498 participants (20.9% women), a total of 229 diabetes cases were reported over a median 3.4 years of follow-up. In the workplace, compared with zero-exposure subjects, the multivariable-adjusted hazard ratios of developing diabetes were 1.81 (95% CI 1.06-3.08, P = 0.028) for present passive subjects and 1.99 (1.29-3.04, P = 0.002) for present active smokers.
CONCLUSIONS: In this cohort, exposure to passive smoke in the workplace was associated with an increased risk of diabetes after adjustment for a large number of possible confounders.
RESEARCH DESIGN AND METHODS: Data were analyzed from a cohort of participants in the High-Risk and Population Strategy for Occupational Health Promotion Study (HIPOP-OHP) conducted in Japan from 1999 to 2004. Active and passive smoking status in the workplace was evaluated at baseline.
RESULTS: Of 6,498 participants (20.9% women), a total of 229 diabetes cases were reported over a median 3.4 years of follow-up. In the workplace, compared with zero-exposure subjects, the multivariable-adjusted hazard ratios of developing diabetes were 1.81 (95% CI 1.06-3.08, P = 0.028) for present passive subjects and 1.99 (1.29-3.04, P = 0.002) for present active smokers.
CONCLUSIONS: In this cohort, exposure to passive smoke in the workplace was associated with an increased risk of diabetes after adjustment for a large number of possible confounders.
PMID: 18235051 [PubMed - indexed for MEDLINE]
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