哮喘控制测试的效度和信度：来自希腊的研究结果
2011/03/28
摘要
背景：在两项对哮喘控制(ACT)测试维度的研究中，得出了相反的结果。目前为止，ACT 尚未在希腊哮喘患者中进行验证。
目的：本试验在希腊专科医生治疗的哮喘门诊患者中研究ACT的效度和信度。
研究设计：基于样本特异性效度的证据，通过构想、横断面、会聚性、区分效度及内部一致性和重测信度(近似值均方根误差[RMSEA])对ACT(n = 100)进行研究。
结果：单因素解决方案适用于这些数据（X2= 3.899，df=5，RMSEA <0.001）。对于所有样本，ACT具有很好的内部一致性（信度系数= 0.72）和2个月内的重测信度（IR = 0.85）。基于专家的评价，ACT结果在5类哮喘控制患者间存在着显著差异（无控制、控制较差、一定程度控制、控制很好、完全控制）(P<0.001)。有和无哮喘控制患者间(P=0.001)、不同性别患者间(P=0.05)、不同教育层次患者间(P=0.05)、不同年收入患者间(P=0.01)、不同体重指数患者间(P=0.05)、不同随访时间患者间(P=0.01)、不同年龄患者间(P<0.001)及不同哮喘严重程度患者间存在显著差异。在筛查未控制哮喘时，ACT评分≤19能最好的平衡敏感性(98.46)和特异性(88.57)。横断面效度检测显示，ACT评分与FEV1%预测值(r = 0.57,P<0.001)和残疾(r = -0.42, P<0.001)存在中度相关性，与呼吸困难之间存在中高度相关(r = -0.71, p < .001)。聚合效度检验显示，ACT评分与专家评价(r = 0.89, P<0.001)相关。
结论：我们的结果显示，在希腊专科医生治疗的哮喘门诊患者中，ACT具有较好的信度和效度。
（苏楠 审校）
J Asthma. 2011 Feb;48(1):57-64. Epub 2010 Nov 1.
Validity and reliability evidence of the asthma control test - act in Greece.
Grammatopoulou EP, Stavrou N, Myrianthefs P, Karteroliotis K, Baltopoulos G, Behrakis P, Koutsouki D.
Department of Physical Education and Sport Sciences, National and Kapodistrian University of Athens, Athens, Greece.
Abstract
Background. The dimensionality of the Asthma Control Test (ACT) was examined in two counterview studies. Up to now, the ACT has not been validated for the Greek asthma patients.
Objective. The present study was designed to examine the validity and reliability of the ACT responses in Greek asthma outpatients under a specialist’s care. Study design. Following evidence for sample-specific validity, the ACT (n = 100) was examined through construct, cross-sectional, convergent, and discriminant validity as well as internal consistency and test-retest reliability [root mean squared error of approximation (RMSEA)].
Results. A one-factor solution fit the data [χ(2) (chi-square) = 3.899, df (degrees of freedom) 5, ns, RMSEA <0.001]. The ACT showed a high internal consistency (Cronbach alpha = 0.72) and a high 2 months test-retest reliability (IR = 0.85) for the total sample. Significant differences were found between the five categories of asthma control patients (not controlled at all, poorly controlled, somewhat controlled, well controlled, and completely controlled), according to the specialists’ rating, for the ACT (p < .001). Significant differences were found between patients with and without asthma control (p = .001), patients of different gender (p = .05), educational status (p = .05), mean year income (p = .01), body mass index (p = .05), follow-up visits (p = .01), as well as among patients of different age (p < .001) and severity (p < .001). An ACT score of 19 or less provided optimum balance of sensitivity (98.46) and specificity (88.57) for screening ’not controlled’ asthma. Cross-sectional validity testing showed moderate correlation of the ACT score with FEV1% predicted (r = 0.57, p < .001) and disability (r = -0.42, p < .001) and moderately high correlation with dyspnea (r = -0.71, p < .001). Convergent validity testing showed that the ACT score was correlated with the specialists’ rating (r = 0.89, p < .001).
Conclusion. The ACT is valid and reliable in Greek outpatients with asthma under a specialist’s care.
J Asthma. 2011 Feb;48(1):57-64. Epub 2010 Nov 1.
背景：在两项对哮喘控制(ACT)测试维度的研究中，得出了相反的结果。目前为止，ACT 尚未在希腊哮喘患者中进行验证。
目的：本试验在希腊专科医生治疗的哮喘门诊患者中研究ACT的效度和信度。
研究设计：基于样本特异性效度的证据，通过构想、横断面、会聚性、区分效度及内部一致性和重测信度(近似值均方根误差[RMSEA])对ACT(n = 100)进行研究。
结果：单因素解决方案适用于这些数据（X2= 3.899，df=5，RMSEA <0.001）。对于所有样本，ACT具有很好的内部一致性（信度系数= 0.72）和2个月内的重测信度（IR = 0.85）。基于专家的评价，ACT结果在5类哮喘控制患者间存在着显著差异（无控制、控制较差、一定程度控制、控制很好、完全控制）(P<0.001)。有和无哮喘控制患者间(P=0.001)、不同性别患者间(P=0.05)、不同教育层次患者间(P=0.05)、不同年收入患者间(P=0.01)、不同体重指数患者间(P=0.05)、不同随访时间患者间(P=0.01)、不同年龄患者间(P<0.001)及不同哮喘严重程度患者间存在显著差异。在筛查未控制哮喘时，ACT评分≤19能最好的平衡敏感性(98.46)和特异性(88.57)。横断面效度检测显示，ACT评分与FEV1%预测值(r = 0.57,P<0.001)和残疾(r = -0.42, P<0.001)存在中度相关性，与呼吸困难之间存在中高度相关(r = -0.71, p < .001)。聚合效度检验显示，ACT评分与专家评价(r = 0.89, P<0.001)相关。
结论：我们的结果显示，在希腊专科医生治疗的哮喘门诊患者中，ACT具有较好的信度和效度。
（苏楠 审校）
J Asthma. 2011 Feb;48(1):57-64. Epub 2010 Nov 1.
Validity and reliability evidence of the asthma control test - act in Greece.
Grammatopoulou EP, Stavrou N, Myrianthefs P, Karteroliotis K, Baltopoulos G, Behrakis P, Koutsouki D.
Department of Physical Education and Sport Sciences, National and Kapodistrian University of Athens, Athens, Greece.
Abstract
Background. The dimensionality of the Asthma Control Test (ACT) was examined in two counterview studies. Up to now, the ACT has not been validated for the Greek asthma patients.
Objective. The present study was designed to examine the validity and reliability of the ACT responses in Greek asthma outpatients under a specialist’s care. Study design. Following evidence for sample-specific validity, the ACT (n = 100) was examined through construct, cross-sectional, convergent, and discriminant validity as well as internal consistency and test-retest reliability [root mean squared error of approximation (RMSEA)].
Results. A one-factor solution fit the data [χ(2) (chi-square) = 3.899, df (degrees of freedom) 5, ns, RMSEA <0.001]. The ACT showed a high internal consistency (Cronbach alpha = 0.72) and a high 2 months test-retest reliability (IR = 0.85) for the total sample. Significant differences were found between the five categories of asthma control patients (not controlled at all, poorly controlled, somewhat controlled, well controlled, and completely controlled), according to the specialists’ rating, for the ACT (p < .001). Significant differences were found between patients with and without asthma control (p = .001), patients of different gender (p = .05), educational status (p = .05), mean year income (p = .01), body mass index (p = .05), follow-up visits (p = .01), as well as among patients of different age (p < .001) and severity (p < .001). An ACT score of 19 or less provided optimum balance of sensitivity (98.46) and specificity (88.57) for screening ’not controlled’ asthma. Cross-sectional validity testing showed moderate correlation of the ACT score with FEV1% predicted (r = 0.57, p < .001) and disability (r = -0.42, p < .001) and moderately high correlation with dyspnea (r = -0.71, p < .001). Convergent validity testing showed that the ACT score was correlated with the specialists’ rating (r = 0.89, p < .001).
Conclusion. The ACT is valid and reliable in Greek outpatients with asthma under a specialist’s care.
J Asthma. 2011 Feb;48(1):57-64. Epub 2010 Nov 1.
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