针灸式经皮神经电刺激对儿童哮喘的影响
2010/11/04
摘要
目的：评价针灸式经皮神经电刺激（AL-TENS）对儿童哮喘的影响。
方法：经过8周的适应期，试验组采用AL-TENS 治疗，而对照则无该处理。对来自医院和小学的43名哮喘患儿进行研究。所有患者均诊断有哮喘。转归检测包括肺功能检测（PFTs）、心率震荡（HRT ）、心率变异性（HRV ）及儿童哮喘生活质量问卷（PAQLQ）。
结果：经过8周的AL-TENS，两组间用力肺活量（FVC）、FEV1/FVC、呼气峰值流量（PEF）无显著差异。HRT是窦房结对室性期前收缩的一个生理性双相反应。试验组，治疗前后平均HRT存在显著差异。HRV与PAQLQ无显著差异。但在试验组，PAQLQ的亚类（特别是活动性）在治疗后显著改善。此外，治疗8周后，两组间在PFTs和HRV无显著差异。
结论：试验组PAQLQ活动性改善显著强于对照组。可能与下列原因有关：(1)患者哮喘稳定或患者处于稳定期；(2)气道重塑程度低。未来的研究中，有必要研究治疗的频率及长期随访，以准确评价AL-TENS对儿童哮喘的影响。
（苏楠 审校）
J Asthma. 2010 Sep 13. [Epub ahead of print]
Effects of acupuncture-like transcutaneous electrical nerve stimulation on children with asthma.
Lin CH, Wang MH, Chung HY, Liu CF.
Department of Nursing, Ching Kuo Institute of Management and Health, Keelung, Taiwan, Republic of China.
Abstract
Objective: To evaluate the effects of acupuncture-like transcutaneous electrical nerve stimulation (AL-TENS) on children with asthma.
Methods: After an 8-week run-in period, the experimental group were assigned to treatment with AL-TENS, whereas the control group did not receive AL-TENS. A total of 43 children with asthma were recruited from a hospital and an elementary school. All the cases had been diagnosed as having asthma by physicians. The outcome measures included pulmonary function tests (PFTs), heart rate turbulence (HRT), heart rate variability (HRV), and pediatric asthma quality-of-life questionnaire (PAQLQ).
Results: After 8 weeks of AL-TENS, there were no significant differences on forced vital capacity (FVC), FEV(1)/FVC, and peak expiratory flows (PEFs) between the two groups. The HRT is the physiological, biphasic response of the sinus node to premature ventricular contractions. In the experimental group, the mean HRT was statistically significant between pretest and posttest. The HRV and the PAQLQ showed no difference, but in the experimental group, the subscale of the PAQLQ (particularly activity) improved significantly more than the pretest scores. Furthermore, there were no differences in PFTs and HRV after 8 weeks of AL-TENS between the two groups.
Conclusions: The PAQLQ activities of the experimental group improved significantly more than those of the control group. Reasons may include: 1) the asthma cases were stable and the cases were on stable status and 2) the degree of airway remodeling was less. It is suggested that in the future, treatment frequency and the long-term follow-up for evaluating the effects of AL-TENS on children with asthma should also be considered.
J Asthma. 2010 Sep 13. [Epub ahead of print]
目的：评价针灸式经皮神经电刺激（AL-TENS）对儿童哮喘的影响。
方法：经过8周的适应期，试验组采用AL-TENS 治疗，而对照则无该处理。对来自医院和小学的43名哮喘患儿进行研究。所有患者均诊断有哮喘。转归检测包括肺功能检测（PFTs）、心率震荡（HRT ）、心率变异性（HRV ）及儿童哮喘生活质量问卷（PAQLQ）。
结果：经过8周的AL-TENS，两组间用力肺活量（FVC）、FEV1/FVC、呼气峰值流量（PEF）无显著差异。HRT是窦房结对室性期前收缩的一个生理性双相反应。试验组，治疗前后平均HRT存在显著差异。HRV与PAQLQ无显著差异。但在试验组，PAQLQ的亚类（特别是活动性）在治疗后显著改善。此外，治疗8周后，两组间在PFTs和HRV无显著差异。
结论：试验组PAQLQ活动性改善显著强于对照组。可能与下列原因有关：(1)患者哮喘稳定或患者处于稳定期；(2)气道重塑程度低。未来的研究中，有必要研究治疗的频率及长期随访，以准确评价AL-TENS对儿童哮喘的影响。
（苏楠 审校）
J Asthma. 2010 Sep 13. [Epub ahead of print]
Effects of acupuncture-like transcutaneous electrical nerve stimulation on children with asthma.
Lin CH, Wang MH, Chung HY, Liu CF.
Department of Nursing, Ching Kuo Institute of Management and Health, Keelung, Taiwan, Republic of China.
Abstract
Objective: To evaluate the effects of acupuncture-like transcutaneous electrical nerve stimulation (AL-TENS) on children with asthma.
Methods: After an 8-week run-in period, the experimental group were assigned to treatment with AL-TENS, whereas the control group did not receive AL-TENS. A total of 43 children with asthma were recruited from a hospital and an elementary school. All the cases had been diagnosed as having asthma by physicians. The outcome measures included pulmonary function tests (PFTs), heart rate turbulence (HRT), heart rate variability (HRV), and pediatric asthma quality-of-life questionnaire (PAQLQ).
Results: After 8 weeks of AL-TENS, there were no significant differences on forced vital capacity (FVC), FEV(1)/FVC, and peak expiratory flows (PEFs) between the two groups. The HRT is the physiological, biphasic response of the sinus node to premature ventricular contractions. In the experimental group, the mean HRT was statistically significant between pretest and posttest. The HRV and the PAQLQ showed no difference, but in the experimental group, the subscale of the PAQLQ (particularly activity) improved significantly more than the pretest scores. Furthermore, there were no differences in PFTs and HRV after 8 weeks of AL-TENS between the two groups.
Conclusions: The PAQLQ activities of the experimental group improved significantly more than those of the control group. Reasons may include: 1) the asthma cases were stable and the cases were on stable status and 2) the degree of airway remodeling was less. It is suggested that in the future, treatment frequency and the long-term follow-up for evaluating the effects of AL-TENS on children with asthma should also be considered.
J Asthma. 2010 Sep 13. [Epub ahead of print]
上一篇：
糠酸莫米松和丙酸氟替卡松治疗青少年和年轻成人哮喘的依从性和哮喘控制
下一篇：
家中口服糖皮质激素，能预防哮喘急诊就诊和住院：我们是否遵循国家指南
