哮喘患者合并症增加患者负担
2010/02/02
目的:比较加拿大成人哮喘患者及健康成人中合并症发生率,并评价哮喘患者合并症与哮喘症状出现和发作之间的关系。
方法:研究数据来自于2005年加拿大社区健康调查(CCHS)。在该项全国性调查中共132,221名加拿大人入选,其中来自加拿大10个省及3个地区的10,089名成人诊断为哮喘。主要分析11个主要慢性合发症。
结果:哮喘患者易发生除恶性肿瘤外的合并症。31%哮喘及合并症患者健康状态一般或较差。哮喘患者,哮喘外的慢性呼吸道疾病、精神疾病及过敏与哮喘症状及其发作显著相关。
结论:加拿大哮喘患者具有较高的合并症发生率。患者需要更多的健康服务及更为复杂的健康管理。医生需及时发现合并症,特别注重对情绪异常及焦虑的处理,因为这些合并症能加重患者哮喘症状,且易被临床医生忽视。
(林江涛 审校)
J Asthma. 2009 Dec; 46(10):1021-1026.
The added burden of comorbidity in patients with asthma.
Zhang T, Carleton BC, Prosser RJ, Smith AM.
Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
OBJECTIVE: Compare the prevalence of comorbidities in adults with and without asthma in Canada and investigate the association between comorbidities in patients with asthma and the occurrence of asthma symptoms or attacks.
METHODS: Survey data from the 2005 Canadian Community Health Survey (CCHS) were analyzed. A total of 132,221 Canadians participated in the national survey; 10,089 adult respondents from 10 Canadian provinces and 3 territories reported having asthma. Analyses focused on 11 major chronic comorbidities.
RESULTS: Respondents with asthma were more likely to have comorbidities except cancer; 31% of respondents with asthma and comorbidities reported their health status to be fair or poor. For respondents with asthma, non-asthma chronic respiratory disease, mental illness, and allergy were significantly associated with having asthma symptoms or attacks.
CONCLUSIONS: Many Canadians with asthma report a high comorbidity burden. These patients will likely require more health services and more complex health management strategies. Comorbid conditions should be clearly identified with particular emphasis on management of mood disorders and anxiety because these conditions are likely to increase asthma symptomatology and may be unrecognized by clinicians.
J Asthma. 2009 Dec; 46(10):1021-1026.
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亚太地区哮喘研究现状:来自PubMed数据库的文献计量学分析
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孕妇哮喘的控制状况和严重度对后代哮喘发病率的影响:两阶段对照研究