哮喘控制与卫生资源利用、工作能力丧失及健康相关生命质量的关系
2009/08/11
目的：研究哮喘控制与健康状况之间的关系。
方法：哮喘患者的横断面数据来自于2006年美国国家健康调查。哮喘控制通过哮喘控制测试检测。健康状况包括工作能力丧失/活动受限、健康相关生命质量、卫生资源利用。哮喘控制对健康状况的影响采用线性和Poisson回归模型分析。
结果：2767名哮喘未得到控制的患者和2912名哮喘得到控制的患者入选本研究。对混杂因素进行校正后，哮喘得到控制的患者具有较高的躯体及精神健康相关生活命质量评分（SF-8）；急诊就诊率降低；住院天数下降；门诊就诊率降低；工作能力丧失者/活动受限者较少。
结论：结果显示，哮喘得到控制与较好的健康状况相关。通过治疗使哮喘控制状况达到最佳，能显著减少直接或间接治疗的费用。
（林江涛 审校）
Williams SA, et al. J Occup Environ Med. 2009 Jun 12. [Epub ahead of print]
The Association Between Asthma Control and Health Care Utilization, Work Productivity Loss and Health-Related Quality of Life.
Williams SA, Wagner S, Kannan H, Bolge SC.
From Health Economics and Outcomes Research (Dr Williams) AstraZeneca LP, Wilmington, Del; and Health Economics and Outcomes Research (Dr Wagner, Dr Kannan, Dr Bolge), Consumer Health Sciences, Princeton, NJ.
OBJECTIVE: To determine the association between asthma control and health outcomes.
METHODS: Cross-sectional data on asthmatic patients were from the 2006 U.S. National Health and Wellness Survey. Asthma control was determined by the Asthma Control Test. Outcomes assessed included work productivity loss/activity impairment, health-related quality of life, and resource utilization. Effects of asthma control on outcomes were determined with linear and Poisson regression models.
RESULTS: There were 2767 uncontrolled asthmatics and 2912 controlled asthmatics. Adjusting for confounders, controlled asthmatics reported (P < 0.001) higher physical and mental health-related quality of life scores (SF-8); fewer emergency room visits, hospitalization days, and medical provider visits; lower levels of overall work productivity loss and activity impairment.
CONCLUSION: Results indicate that asthma control is associated with better health outcomes. Management with therapies optimizing asthma control may reduce direct and indirect costs of treatment.
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儿童哮喘严重性与接触室内常见的灰尘过敏原之间的关系
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英国1958年出生人口中哮喘危险因素与原位克隆哮喘易感基因的多态性之间的关系
