哮喘联盟

    目的：本研究的目的是从多角度评价成人哮喘患者生命质量(QOL)与疾病控制、症状困扰、功能之间的关系。
    方法：采用横断面研究，使用邮寄调查设计。172例支气管哮喘患者入选本研究。用生命质量指数－肺第三版(QLI-PV III)评价生命质量，概念化的主观生活满意度。用哮喘调查问卷(LWAQ)评价功能。开发了测量哮喘控制情况和症状的仪器并用于这项研究。用多元回归和路径分析来研究相互关系。
    结果：功能直接影响QOL(β=-0.70)。哮喘控制情况和症状困扰间接影响生命质量。在预测中，哮喘控制情况和功能(γ=0.20)以及症状困扰和功能(γ=0.57)之间有直接关联；51％的功能变化与症状困扰和哮喘控制情况有关; 48％QOL改变与功能有关。
    结论：结果强调了症状困扰和控制哮喘症状对于患者QOL和功能的重要性。

（林江涛 审校）
Oh EG. J Asthma. 2008 Dec;45(10):882-886.

The relationship between disease control, symptom distress, functioning, and quality of life in adults with asthma.

Oh EG.
College of Nursing, Yonsei University, Seodaemun-Gu, Seoul, Republic of Korea.

Purpose: The purpose of this study was to evaluate quality of life (QOL) from a multidimensional perspective in relation to asthma control, symptom distress, and functioning in adults with asthma.
Methods: A cross-sectional, mailing survey design was used. The convenience sample of 172 people diagnosed with asthma participated in this study. QOL, conceptualized as subjective satisfaction with life, was measured by the Quality of Life Index-Pulmonary Version III (QLI-PV III). Functioning was measured with the Living with Asthma Questionnaire (LWAQ). Instruments measuring asthma control and symptom experience have been developed for this study. Multiple regression and path analysis were used to examine the relationships.
Results: The QOL was affected directly by functioning (beta = -0.70). Asthma control and symptom distress were indirectly influencing QOL. Among the predictors, direct paths were found between asthma control and functioning (gamma = 0.20), and between symptom distress and functioning (gamma = 0.57); 51% of the total variation in functioning was explained by symptom distress and asthma control; 48% of the total variation in QOL was explained by functioning.

Conclusion: The findings highlight the importance of symptom distress and control of asthma symptoms with respect to functioning and QOL in people with asthma.