香港青少年哮喘症状与主动和被动吸烟的关系
2012/04/06
背景:吸烟会对呼吸系统产生有害作用。本试验在香港青少年中研究主动和被动吸烟与哮喘症状之间的关系。
方法:有6494名平均年龄为15岁的香港中学学生参与2000~2001健康相关行为一般调查(HRBG)。通过问卷调查,记录参与者的人口统计学信息(性别、年龄、住房类型、生活区域)、生活方式(吸烟、饮酒、课外体育运动和饮食)、哮喘症状(运动诱发的支气管痉挛[EIB]、夜间咳嗽)。此外,记录父母吸烟人数(无/一个/两个)、是否有吸烟的挚友(有/无)。Logistic回归模型在对人口统计学因素和生活方式校正后,分析不同吸烟状态学生、父母和挚友经常出现哮喘症状的优势比(OR)。
结果:以前吸烟者、轻度吸烟者和重度吸烟者的比例分别为17.5%、7.7%和1.0%。此外,35.1%的参与者父母其中之一吸烟,3.8%的参与者父母均吸烟。与不吸烟者相比,重度吸烟者更有可能出现EIB(OR 2.27,95%CI:1.30-3.97)、夜间咳嗽(3.45,1.52-7.81)或两者同时出现(4.69,1.88-11.73)。与无父母吸烟和无吸烟挚友的参与者相比,父母至少一个吸烟和一个吸烟挚友的参与者,其相应的OR分别为1.45(1.17-1.81)、1.61(1.06-2.42)和2.43(1.37-4.31)。
结论:重度吸烟的青少年和父母吸烟或有吸烟挚友的青少年,更有可能出现哮喘症状。
(刘国梁 审校)
Respir Care. 2012 Feb 17. [Epub ahead of print]
The Associations of Asthma Symptoms With Active and Passive Smoking in Hong Kong Adolescents.
Mak KK, Ho RC, Day JR.
Abstract
BACKGROUND: Tobacco smoke has detrimental effects on the respiratory system. This study investigated the associations of active and passive smoking with asthma symptoms in Hong Kong adolescents.
METHODS: A total of 6,494 Hong Kong secondary school students with mean age of 15.0 (SD=1.21) participated in the Health Related Behavior General (HRBG) Survey in 2000-2001. They reported their demographic factors (sex, age, housing type, district of living), lifestyles (smoking, drinking, extracurricular sports, eating), and asthma symptoms (exercise-induced bronchospasm (EIB) and nocturnal cough) in the questionnaire. In addition, number of smoking parents (none/one/both) and presence of a smoking best friend (yes/no) were assessed. Logistic regression models were used to determine the odds ratios (OR) of frequently having the asthma symptoms for different smoking status of students, parents, and best friend with adjustment for demographic factors and lifestyles.
RESULTS: The prevalence of former, light, and heavy smokers was 17.5%, 7.7%, and 1.0%, respectively. Moreover, 35.1% of the participants had one and 3.8% had two parents who smoked. Heavy smokers were more likely to experience EIB with OR (95%CI) of 2.27 (1.30-3.97) and nocturnal cough with OR (95%CI) of 3.45 (1.52-7.81), as well as both symptoms with OR (95%CI)=4.69 (1.88-11.73) when compared to those who never smoked. The corresponding OR (95%CI) for having at least one smoking parent and a smoking best friend was 1.45 (1.17-1.81), 1.61 (1.06-2.42), and 2.43 (1.37-4.31), when compared with those without a parent or best friend who smoked.
CONCLUSION: Adolescents who are heavy smokers and having parents and a best friend who smoke are more likely to have asthma symptoms than others.
Respir Care. 2012 Feb 17. [Epub ahead of print]
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COPD吸烟者特征与药物戒烟的有效性和安全性
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围手术期戒烟